BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000117399 CDC20 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.946785 View
ENSG00000089157 RPLP0 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.946733 View
ENSG00000157764 BRAF ENSG00000158828 PINK1 H. sapiens SSL Slorth 0.946723 View
ENSG00000102572 STK24 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.946436 View
ENSG00000157764 BRAF ENSG00000172059 KLF11 H. sapiens SDL Slorth 0.946404 View
ENSG00000105974 CAV1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.946219 View
ENSG00000157764 BRAF ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.946213 View
ENSG00000157764 BRAF ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.946133 View
ENSG00000096968 JAK2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.945933 View
ENSG00000072736 NFATC3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.945888 View
ENSG00000157764 BRAF ENSG00000185591 SP1 H. sapiens SSL Slorth 0.945859 View
ENSG00000135521 LTV1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.945818 View
ENSG00000070831 CDC42 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.945623 View
ENSG00000156482 RPL30 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.945533 View
ENSG00000132341 RAN ENSG00000157764 BRAF H. sapiens SDL Slorth 0.945483 View
ENSG00000105568 PPP2R1A ENSG00000157764 BRAF H. sapiens SDL Slorth 0.945389 View
ENSG00000044574 HSPA5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.945377 View
ENSG00000115808 STRN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.945376 View
ENSG00000157764 BRAF ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.945279 View
ENSG00000157764 BRAF ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.945278 View
ENSG00000157764 BRAF ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.945222 View
ENSG00000104695 PPP2CB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.945098 View
ENSG00000157764 BRAF ENSG00000169750 RAC3 H. sapiens SDL Slorth 0.94497 View
ENSG00000157764 BRAF ENSG00000187741 FANCA H. sapiens SSL Slorth 0.944968 View
ENSG00000157764 BRAF ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.944716 View
ENSG00000130382 MLLT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.9445 View
ENSG00000157764 BRAF ENSG00000166341 DCHS1 H. sapiens SDL Slorth 0.944474 View
ENSG00000141564 RPTOR ENSG00000157764 BRAF H. sapiens SDL Slorth 0.944455 View
ENSG00000072803 FBXW11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.944423 View
ENSG00000157764 BRAF ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.944345 View
ENSG00000157764 BRAF ENSG00000171105 INSR H. sapiens SSL Slorth 0.944227 View
ENSG00000124164 VAPB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.94418 View
ENSG00000010810 FYN ENSG00000157764 BRAF H. sapiens SDL Slorth 0.944114 View
ENSG00000145715 RASA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.944068 View
ENSG00000157764 BRAF ENSG00000166913 YWHAB H. sapiens SSL Slorth 0.944056 View
ENSG00000157764 BRAF ENSG00000197694 SPTAN1 H. sapiens SSL Slorth 0.944036 View
ENSG00000134057 CCNB1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.943998 View
ENSG00000050820 BCAR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943926 View
ENSG00000116039 ATP6V1B1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943867 View
ENSG00000141543 EIF4A3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943865 View