RAN - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAN	ENSG00000132341	No diseases in record	No drugs in record	chromatin binding transcription coactivator activity GTPase activity protein binding GTP binding GDP binding androgen receptor binding cadherin binding involved in cell-cell adhesion protein transmembrane transporter activity pre-miRNA binding pre-miRNA transporter activity	GSP1 (S. cerevisiae) GSP2 (S. cerevisiae) Ran (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)