ATM - BRAF

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ATM ENSG00000149311 T-PLL
leukaemia
lymphoma
medulloblastoma
glioma

No drugs in record

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding
TEL1 (S. cerevisiae)
tefu (D. melanogaster)
BRAF ENSG00000157764 melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric
DABRAFENIB
REGORAFENIB
SORAFENIB
VEMURAFENIB
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
small GTPase binding
lin-45 (C. elegans)