STK11 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
STK11	ENSG00000118046	NSCLC pancreatic jejunal hamartoma ovarian testicular	No drugs in record	magnesium ion binding p53 binding protein serine/threonine kinase activity protein binding ATP binding LRR domain binding protein kinase activator activity	SAK1 (S. cerevisiae) TOS3 (S. cerevisiae) par-4 (C. elegans) lkb1 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)