PDGFRA

ENSG00000134853 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005018 platelet-derived growth factor alpha-receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0038085 vascular endothelial growth factor binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000119048 UBE2B ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.847216 View
ENSG00000134853 PDGFRA ENSG00000198087 CD2AP H. sapiens SSL Slorth 0.846844 View
ENSG00000110330 BIRC2 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.844977 View
ENSG00000114062 UBE3A ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.844766 View
ENSG00000105568 PPP2R1A ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.844632 View
ENSG00000134853 PDGFRA ENSG00000147162 OGT H. sapiens SSL Slorth 0.843848 View
ENSG00000049759 NEDD4L ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.842642 View
ENSG00000134853 PDGFRA ENSG00000170315 UBB H. sapiens SSL Slorth 0.841172 View
ENSG00000001626 CFTR ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.840785 View
ENSG00000107581 EIF3A ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.840195 View
ENSG00000134853 PDGFRA ENSG00000173039 RELA H. sapiens SSL Slorth 0.839796 View
ENSG00000134853 PDGFRA ENSG00000136238 RAC1 H. sapiens SSL Slorth 0.839791 View
ENSG00000134853 PDGFRA ENSG00000166266 CUL5 H. sapiens SSL Slorth 0.837926 View
ENSG00000070950 RAD18 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.835667 View
ENSG00000110713 NUP98 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.833196 View
ENSG00000104738 MCM4 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.832753 View
ENSG00000101412 E2F1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.831865 View
ENSG00000134853 PDGFRA ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.830408 View
ENSG00000134853 PDGFRA ENSG00000170144 HNRNPA3 H. sapiens SSL Slorth 0.830062 View
ENSG00000085840 ORC1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.830025 View
ENSG00000134853 PDGFRA ENSG00000138668 HNRNPD H. sapiens SSL Slorth 0.829704 View
ENSG00000102978 POLR2C ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.829558 View
ENSG00000134853 PDGFRA ENSG00000139687 RB1 H. sapiens SSL Slorth 0.828592 View
ENSG00000134853 PDGFRA ENSG00000134987 WDR36 H. sapiens SSL Slorth 0.82858 View
ENSG00000134853 PDGFRA ENSG00000159461 AMFR H. sapiens SSL Slorth 0.827817 View
ENSG00000132383 RPA1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.826558 View
ENSG00000106462 EZH2 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.82621 View
ENSG00000117748 RPA2 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.822991 View
ENSG00000099804 CDC34 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.821571 View
ENSG00000134853 PDGFRA ENSG00000167461 RAB8A H. sapiens SSL Slorth 0.820599 View
ENSG00000115816 CEBPZ ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.820291 View
ENSG00000134853 PDGFRA ENSG00000183765 CHEK2 H. sapiens SSL Slorth 0.819034 View
ENSG00000134853 PDGFRA ENSG00000143106 PSMA5 H. sapiens SSL Slorth 0.818904 View
ENSG00000134853 PDGFRA ENSG00000158828 PINK1 H. sapiens SSL Slorth 0.818024 View
ENSG00000070756 PABPC1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.81701 View
ENSG00000044574 HSPA5 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.816158 View
ENSG00000006451 RALA ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.815729 View
ENSG00000134853 PDGFRA ENSG00000198561 CTNND1 H. sapiens SSL Slorth 0.815225 View
ENSG00000134853 PDGFRA ENSG00000185591 SP1 H. sapiens SSL Slorth 0.811609 View
ENSG00000134853 PDGFRA ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.810907 View