EZH2 - PDGFRA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EZH2	ENSG00000106462	DLBCL	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding core promoter binding DNA binding chromatin binding protein binding protein-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity chromatin DNA binding histone methyltransferase activity ribonucleoprotein complex binding histone methyltransferase activity (H3-K27 specific) primary miRNA binding promoter-specific chromatin binding	SET2 (S. cerevisiae) lin-59 (C. elegans) E(z) (D. melanogaster)
PDGFRA	ENSG00000134853	GIST idiopathic hypereosinophilic syndrome paediatric glioblastoma	BECAPLERMIN LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB SUNITINIB	protein kinase activity transmembrane receptor protein tyrosine kinase activity platelet-derived growth factor alpha-receptor activity vascular endothelial growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding ATP binding vascular endothelial growth factor binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)