PDGFRA

ENSG00000134853 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005018 platelet-derived growth factor alpha-receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0038085 vascular endothelial growth factor binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000134853 PDGFRA ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.964747 View
ENSG00000134853 PDGFRA ENSG00000146648 EGFR H. sapiens SDL Slorth 0.964513 View
ENSG00000134853 PDGFRA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964378 View
ENSG00000133703 KRAS ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.96411 View
ENSG00000134853 PDGFRA ENSG00000185359 HGS H. sapiens SSL Slorth 0.963904 View
ENSG00000134853 PDGFRA ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.963894 View
ENSG00000134853 PDGFRA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.963837 View
ENSG00000134853 PDGFRA ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.963765 View
ENSG00000134853 PDGFRA ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.963421 View
ENSG00000134853 PDGFRA ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.963357 View
ENSG00000134853 PDGFRA ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.962579 View
ENSG00000134853 PDGFRA ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.962317 View
ENSG00000134853 PDGFRA ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.962095 View
ENSG00000134853 PDGFRA ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.961969 View
ENSG00000134853 PDGFRA ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.961848 View
ENSG00000124762 CDKN1A ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.961446 View
ENSG00000134853 PDGFRA ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.960861 View
ENSG00000097007 ABL1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.960724 View
ENSG00000103275 UBE2I ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.960619 View
ENSG00000134853 PDGFRA ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.960602 View
ENSG00000134853 PDGFRA ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.960381 View
ENSG00000134853 PDGFRA ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.960304 View
ENSG00000134853 PDGFRA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.960136 View
ENSG00000134853 PDGFRA ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.959876 View
ENSG00000082898 XPO1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.959684 View
ENSG00000134853 PDGFRA ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.959352 View
ENSG00000134853 PDGFRA ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.959302 View
ENSG00000134853 PDGFRA ENSG00000149311 ATM H. sapiens SSL Slorth 0.959272 View
ENSG00000132155 RAF1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.959218 View
ENSG00000134853 PDGFRA ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.959122 View
ENSG00000116030 SUMO1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.958491 View
ENSG00000134853 PDGFRA ENSG00000187555 USP7 H. sapiens SSL Slorth 0.95842 View
ENSG00000134853 PDGFRA ENSG00000254087 LYN H. sapiens SSL Slorth 0.958146 View
ENSG00000134853 PDGFRA ENSG00000166200 COPS2 H. sapiens SSL Slorth 0.957726 View
ENSG00000134853 PDGFRA ENSG00000141543 EIF4A3 H. sapiens SSL Slorth 0.957624 View
ENSG00000134853 PDGFRA ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.95762 View
ENSG00000134853 PDGFRA ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.957378 View
ENSG00000134853 PDGFRA ENSG00000153147 SMARCA5 H. sapiens SSL Slorth 0.957331 View
ENSG00000134853 PDGFRA ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.957176 View
ENSG00000134853 PDGFRA ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.957145 View