PDGFRA

ENSG00000134853 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005018 platelet-derived growth factor alpha-receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0038085 vascular endothelial growth factor binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000134853 PDGFRA ENSG00000166226 CCT2 H. sapiens SSL Slorth 0.947168 View
ENSG00000134853 PDGFRA ENSG00000135341 MAP3K7 H. sapiens SSL Slorth 0.947163 View
ENSG00000134853 PDGFRA ENSG00000136518 ACTL6A H. sapiens SSL Slorth 0.946802 View
ENSG00000134853 PDGFRA ENSG00000149136 SSRP1 H. sapiens SSL Slorth 0.946436 View
ENSG00000103275 UBE2I ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.946236 View
ENSG00000010810 FYN ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.946074 View
ENSG00000097046 CDC7 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.946003 View
ENSG00000080824 HSP90AA1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.945991 View
ENSG00000113575 PPP2CA ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.945979 View
ENSG00000134853 PDGFRA ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.945889 View
ENSG00000134853 PDGFRA ENSG00000136628 EPRS H. sapiens SSL Slorth 0.94532 View
ENSG00000134853 PDGFRA ENSG00000150753 CCT5 H. sapiens SSL Slorth 0.945176 View
ENSG00000134853 PDGFRA ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.944 View
ENSG00000134853 PDGFRA ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.943838 View
ENSG00000134853 PDGFRA ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.94356 View
ENSG00000134853 PDGFRA ENSG00000186716 BCR H. sapiens SSL Slorth 0.943001 View
ENSG00000134853 PDGFRA ENSG00000137693 YAP1 H. sapiens SSL Slorth 0.942732 View
ENSG00000089159 PXN ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.94232 View
ENSG00000134853 PDGFRA ENSG00000163938 GNL3 H. sapiens SSL Slorth 0.942227 View
ENSG00000134853 PDGFRA ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.942037 View
ENSG00000134853 PDGFRA ENSG00000179262 RAD23A H. sapiens SSL Slorth 0.941294 View
ENSG00000112592 TBP ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.941082 View
ENSG00000134853 PDGFRA ENSG00000141027 NCOR1 H. sapiens SSL Slorth 0.940962 View
ENSG00000134853 PDGFRA ENSG00000150093 ITGB1 H. sapiens SSL Slorth 0.940435 View
ENSG00000100030 MAPK1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.940326 View
ENSG00000121022 COPS5 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.940038 View
ENSG00000134853 PDGFRA ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.939887 View
ENSG00000134853 PDGFRA ENSG00000213341 CHUK H. sapiens SSL Slorth 0.939708 View
ENSG00000134853 PDGFRA ENSG00000148606 POLR3A H. sapiens SSL Slorth 0.939475 View
ENSG00000134853 PDGFRA ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.939317 View
ENSG00000113721 PDGFRB ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.938671 View
ENSG00000134853 PDGFRA ENSG00000165025 SYK H. sapiens SSL Slorth 0.938374 View
ENSG00000134853 PDGFRA ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.937981 View
ENSG00000110395 CBL ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.93781 View
ENSG00000004700 RECQL ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.93769 View
ENSG00000096968 JAK2 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.937461 View
ENSG00000134853 PDGFRA ENSG00000171105 INSR H. sapiens SSL Slorth 0.937358 View
ENSG00000134853 PDGFRA ENSG00000135624 CCT7 H. sapiens SSL Slorth 0.937099 View
ENSG00000134853 PDGFRA ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.935829 View
ENSG00000134853 PDGFRA ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.935127 View