PDGFRA

ENSG00000134853 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005018 platelet-derived growth factor alpha-receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0038085 vascular endothelial growth factor binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000050820 BCAR1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.91442 View
ENSG00000094804 CDC6 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.914101 View
ENSG00000124181 PLCG1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.913553 View
ENSG00000128245 YWHAH ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.913207 View
ENSG00000111276 CDKN1B ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.913141 View
ENSG00000073111 MCM2 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.912396 View
ENSG00000072401 UBE2D1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.912392 View
ENSG00000134853 PDGFRA ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.912363 View
ENSG00000105974 CAV1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.911936 View
ENSG00000134853 PDGFRA ENSG00000185591 SP1 H. sapiens SDL Slorth 0.911631 View
ENSG00000134853 PDGFRA ENSG00000165280 VCP H. sapiens SSL Slorth 0.910716 View
ENSG00000134853 PDGFRA ENSG00000140464 PML H. sapiens SSL Slorth 0.91011 View
ENSG00000069869 NEDD4 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.909584 View
ENSG00000134853 PDGFRA ENSG00000198554 WDHD1 H. sapiens SSL Slorth 0.909433 View
ENSG00000104365 IKBKB ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.908199 View
ENSG00000134853 PDGFRA ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.907735 View
ENSG00000134853 PDGFRA ENSG00000197694 SPTAN1 H. sapiens SSL Slorth 0.907138 View
ENSG00000100644 HIF1A ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.906527 View
ENSG00000100906 NFKBIA ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.90604 View
ENSG00000134853 PDGFRA ENSG00000273841 TAF9 H. sapiens SSL Slorth 0.905216 View
ENSG00000134853 PDGFRA ENSG00000167085 PHB H. sapiens SSL Slorth 0.904325 View
ENSG00000134853 PDGFRA ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.903956 View
ENSG00000134853 PDGFRA ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.903388 View
ENSG00000134853 PDGFRA ENSG00000166598 HSP90B1 H. sapiens SSL Slorth 0.903081 View
ENSG00000134853 PDGFRA ENSG00000160691 SHC1 H. sapiens SSL Slorth 0.902453 View
ENSG00000134853 PDGFRA ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.90227 View
ENSG00000127022 CANX ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.901907 View
ENSG00000134853 PDGFRA ENSG00000187735 TCEA1 H. sapiens SSL Slorth 0.901814 View
ENSG00000096384 HSP90AB1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.900856 View
ENSG00000134853 PDGFRA ENSG00000174775 HRAS H. sapiens SSL Slorth 0.899484 View
ENSG00000109971 HSPA8 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.898928 View
ENSG00000134853 PDGFRA ENSG00000134954 ETS1 H. sapiens SSL Slorth 0.896678 View
ENSG00000134853 PDGFRA ENSG00000175054 ATR H. sapiens SSL Slorth 0.896612 View
ENSG00000134853 PDGFRA ENSG00000135829 DHX9 H. sapiens SSL Slorth 0.896569 View
ENSG00000101966 XIAP ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.895898 View
ENSG00000134853 PDGFRA ENSG00000170004 CHD3 H. sapiens SSL Slorth 0.895842 View
ENSG00000134853 PDGFRA ENSG00000160803 UBQLN4 H. sapiens SSL Slorth 0.895617 View
ENSG00000134853 PDGFRA ENSG00000176105 YES1 H. sapiens SSL Slorth 0.895463 View
ENSG00000134853 PDGFRA ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.893738 View
ENSG00000133316 WDR74 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.893469 View