PDGFRA

ENSG00000134853 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005018 platelet-derived growth factor alpha-receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0038085 vascular endothelial growth factor binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000134853 PDGFRA ENSG00000162298 SYVN1 H. sapiens SSL Slorth 0.934958 View
ENSG00000134853 PDGFRA ENSG00000167552 TUBA1A H. sapiens SSL Slorth 0.934881 View
ENSG00000010810 FYN ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.934545 View
ENSG00000134853 PDGFRA ENSG00000283094 PTEN H. sapiens SSL Slorth 0.934363 View
ENSG00000128052 KDR ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.93434 View
ENSG00000134853 PDGFRA ENSG00000168090 COPS6 H. sapiens SSL Slorth 0.934263 View
ENSG00000096717 SIRT1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.934216 View
ENSG00000134853 PDGFRA ENSG00000171720 HDAC3 H. sapiens SDL Slorth 0.933728 View
ENSG00000091831 ESR1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.932433 View
ENSG00000091831 ESR1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.932185 View
ENSG00000134853 PDGFRA ENSG00000141367 CLTC H. sapiens SSL Slorth 0.931848 View
ENSG00000097007 ABL1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.930875 View
ENSG00000112062 MAPK14 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.930625 View
ENSG00000082701 GSK3B ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.930587 View
ENSG00000113558 SKP1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.930124 View
ENSG00000131759 RARA ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.930106 View
ENSG00000132155 RAF1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.929376 View
ENSG00000134853 PDGFRA ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.928962 View
ENSG00000134853 PDGFRA ENSG00000158092 NCK1 H. sapiens SDL Slorth 0.928772 View
ENSG00000077782 FGFR1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.928425 View
ENSG00000092820 EZR ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.928385 View
ENSG00000134853 PDGFRA ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.927141 View
ENSG00000132646 PCNA ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.92418 View
ENSG00000134853 PDGFRA ENSG00000170248 PDCD6IP H. sapiens SSL Slorth 0.924096 View
ENSG00000134853 PDGFRA ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.923446 View
ENSG00000134853 PDGFRA ENSG00000173039 RELA H. sapiens SDL Slorth 0.921955 View
ENSG00000101146 RAE1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.921835 View
ENSG00000134853 PDGFRA ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.921302 View
ENSG00000101868 POLA1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.92087 View
ENSG00000134853 PDGFRA ENSG00000164362 TERT H. sapiens SSL Slorth 0.920169 View
ENSG00000121774 KHDRBS1 ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.919334 View
ENSG00000134853 PDGFRA ENSG00000136937 NCBP1 H. sapiens SSL Slorth 0.918736 View
ENSG00000124762 CDKN1A ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.918637 View
ENSG00000134853 PDGFRA ENSG00000143093 STRIP1 H. sapiens SSL Slorth 0.917385 View
ENSG00000134853 PDGFRA ENSG00000254772 EEF1G H. sapiens SSL Slorth 0.916167 View
ENSG00000134853 PDGFRA ENSG00000172534 HCFC1 H. sapiens SSL Slorth 0.916078 View
ENSG00000134853 PDGFRA ENSG00000178999 AURKB H. sapiens SSL Slorth 0.916047 View
ENSG00000117399 CDC20 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.915617 View
ENSG00000134853 PDGFRA ENSG00000164305 CASP3 H. sapiens SSL Slorth 0.91532 View
ENSG00000134853 PDGFRA ENSG00000169398 PTK2 H. sapiens SDL Slorth 0.914716 View