PDGFRA - AMFR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRA	ENSG00000134853	GIST idiopathic hypereosinophilic syndrome paediatric glioblastoma	BECAPLERMIN LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB SUNITINIB	protein kinase activity transmembrane receptor protein tyrosine kinase activity platelet-derived growth factor alpha-receptor activity vascular endothelial growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding ATP binding vascular endothelial growth factor binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
AMFR	ENSG00000159461	No diseases in record	No drugs in record	ubiquitin-protein transferase activity receptor activity protein binding zinc ion binding protein binding, bridging ubiquitin-ubiquitin ligase activity chaperone binding ubiquitin protein ligase activity ubiquitin protein ligase activity involved in ERAD pathway BAT3 complex binding ubiquitin-specific protease binding	HRD1 (S. cerevisiae) hrdl-1 (C. elegans)