Go term | Description |
---|---|
GO:0001042 | RNA polymerase I core binding |
GO:0004713 | protein tyrosine kinase activity |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity |
GO:0004716 | signal transducer, downstream of receptor, with protein tyrosine kinase activity |
GO:0004888 | transmembrane signaling receptor activity |
GO:0005088 | Ras guanyl-nucleotide exchange factor activity |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0008022 | protein C-terminus binding |
GO:0019903 | protein phosphatase binding |
GO:0042802 | identical protein binding |
GO:0043125 | ErbB-3 class receptor binding |
GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
GO:0046982 | protein heterodimerization activity |
GO:0046983 | protein dimerization activity |
GO:0019838 | growth factor binding |
Drug name | Description |
---|---|
AFATINIB | Epidermal growth factor receptor erbB1 inhibitor |
LAPATINIB | Epidermal growth factor receptor erbB1 inhibitor |
PERTUZUMAB | Receptor protein-tyrosine kinase erbB-2 inhibitor |
TRASTUZUMAB | Receptor protein-tyrosine kinase erbB-2 inhibitor |
TRASTUZUMAB EMTANSINE | Tubulin inhibitor |
VANDETANIB | Epidermal growth factor receptor inhibitor |
Disease Name |
---|
breast |
ovarian |
other tumour types |
NSCLC |
gastric |
Gene | Organism | |
---|---|---|
let-23 | C. elegans | |
Egfr | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000141736 | ERBB2 | ENSG00000169750 | RAC3 | H. sapiens | SSL | Slorth | 0.968002 | View |
ENSG00000124181 | PLCG1 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.96778 | View |
ENSG00000141736 | ERBB2 | ENSG00000160145 | KALRN | H. sapiens | SDL | Slorth | 0.967738 | View |
ENSG00000128245 | YWHAH | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.967632 | View |
ENSG00000141736 | ERBB2 | ENSG00000180176 | TH | H. sapiens | SDL | Slorth | 0.967511 | View |
ENSG00000073111 | MCM2 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.967495 | View |
ENSG00000141736 | ERBB2 | ENSG00000149136 | SSRP1 | H. sapiens | SSL | Slorth | 0.967437 | View |
ENSG00000089159 | PXN | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.967389 | View |
ENSG00000072736 | NFATC3 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.967384 | View |
ENSG00000141736 | ERBB2 | ENSG00000163743 | RCHY1 | H. sapiens | SSL | Slorth | 0.967232 | View |
ENSG00000109906 | ZBTB16 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.966985 | View |
ENSG00000141736 | ERBB2 | ENSG00000213923 | CSNK1E | H. sapiens | SSL | Slorth | 0.966861 | View |
ENSG00000070950 | RAD18 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.96682 | View |
ENSG00000141736 | ERBB2 | ENSG00000159461 | AMFR | H. sapiens | SSL | Slorth | 0.966819 | View |
ENSG00000127511 | SIN3B | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.966801 | View |
ENSG00000021574 | SPAST | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.966726 | View |
ENSG00000091831 | ESR1 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.966639 | View |
ENSG00000132341 | RAN | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.9665 | View |
ENSG00000103126 | AXIN1 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.966376 | View |
ENSG00000110395 | CBL | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.966362 | View |
ENSG00000141736 | ERBB2 | ENSG00000169554 | ZEB2 | H. sapiens | SDL | Slorth | 0.966353 | View |
ENSG00000141736 | ERBB2 | ENSG00000188021 | UBQLN2 | H. sapiens | SSL | Slorth | 0.966306 | View |
ENSG00000141736 | ERBB2 | ENSG00000153487 | ING1 | H. sapiens | SSL | Slorth | 0.966275 | View |
ENSG00000070010 | UFD1L | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.966167 | View |
ENSG00000061918 | GUCY1B3 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.966136 | View |
ENSG00000119048 | UBE2B | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.966098 | View |
ENSG00000141736 | ERBB2 | ENSG00000169047 | IRS1 | H. sapiens | SSL | Slorth | 0.966065 | View |
ENSG00000105290 | APLP1 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.966044 | View |
ENSG00000141736 | ERBB2 | ENSG00000213949 | ITGA1 | H. sapiens | SDL | Slorth | 0.966029 | View |
ENSG00000141736 | ERBB2 | ENSG00000169375 | SIN3A | H. sapiens | SSL | Slorth | 0.965937 | View |
ENSG00000099785 | MARCH2 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.965785 | View |
ENSG00000135604 | STX11 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.965767 | View |
ENSG00000113721 | PDGFRB | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.965672 | View |
ENSG00000141736 | ERBB2 | ENSG00000182511 | FES | H. sapiens | SDL | Slorth | 0.965656 | View |
ENSG00000141736 | ERBB2 | ENSG00000180008 | SOCS4 | H. sapiens | SDL | Slorth | 0.965621 | View |
ENSG00000138376 | BARD1 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.9656 | View |
ENSG00000141736 | ERBB2 | ENSG00000154310 | TNIK | H. sapiens | SDL | Slorth | 0.965509 | View |
ENSG00000141736 | ERBB2 | ENSG00000184675 | AMER1 | H. sapiens | SDL | Slorth | 0.965492 | View |
ENSG00000141736 | ERBB2 | ENSG00000169047 | IRS1 | H. sapiens | SDL | Slorth | 0.965479 | View |
ENSG00000141736 | ERBB2 | ENSG00000196419 | XRCC6 | H. sapiens | SSL | Slorth | 0.96544 | View |