GUCY1B3 - ERBB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GUCY1B3	ENSG00000061918	No diseases in record	ISOSORBIDE DINITRATE ISOSORBIDE MONONITRATE NITRIC OXIDE NITROGLYCERIN NITROPRUSSIDE RIOCIGUAT	guanylate cyclase activity receptor activity protein binding GTP binding heme binding metal ion binding adenylate cyclase activity	No GO terms in record
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)