SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143569 UBAP2L ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977805 View
ENSG00000165525 NEMF ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977804 View
ENSG00000166949 SMAD3 ENSG00000178188 SH2B1 H. sapiens SDL Slorth 0.977757 View
ENSG00000166949 SMAD3 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.977742 View
ENSG00000116729 WLS ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977739 View
ENSG00000135090 TAOK3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977722 View
ENSG00000166949 SMAD3 ENSG00000181789 COPG1 H. sapiens SDL Slorth 0.977719 View
ENSG00000166949 SMAD3 ENSG00000186432 KPNA4 H. sapiens SDL Slorth 0.977702 View
ENSG00000077943 ITGA8 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977696 View
ENSG00000166949 SMAD3 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.977675 View
ENSG00000115993 TRAK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977674 View
ENSG00000166949 SMAD3 ENSG00000178950 GAK H. sapiens SDL Slorth 0.977664 View
ENSG00000081913 PHLPP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977642 View
ENSG00000166949 SMAD3 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.977637 View
ENSG00000137073 UBAP2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977626 View
ENSG00000130522 JUND ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977603 View
ENSG00000166949 SMAD3 ENSG00000171094 ALK H. sapiens SDL Slorth 0.977596 View
ENSG00000166949 SMAD3 ENSG00000254087 LYN H. sapiens SDL Slorth 0.977594 View
ENSG00000143252 SDHC ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977576 View
ENSG00000119396 RAB14 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977571 View
ENSG00000100968 NFATC4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977562 View
ENSG00000166949 SMAD3 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.977562 View
ENSG00000063660 GPC1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977559 View
ENSG00000048462 TNFRSF17 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977559 View
ENSG00000100505 TRIM9 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977549 View
ENSG00000166949 SMAD3 ENSG00000198561 CTNND1 H. sapiens SDL Slorth 0.977533 View
ENSG00000127527 EPS15L1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977532 View
ENSG00000165684 SNAPC4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977511 View
ENSG00000166949 SMAD3 ENSG00000170759 KIF5B H. sapiens SDL Slorth 0.977499 View
ENSG00000166949 SMAD3 ENSG00000182872 RBM10 H. sapiens SDL Slorth 0.977495 View
ENSG00000166949 SMAD3 ENSG00000175634 RPS6KB2 H. sapiens SDL Slorth 0.977461 View
ENSG00000131437 KIF3A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977458 View
ENSG00000101350 KIF3B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977458 View
ENSG00000166949 SMAD3 ENSG00000254445 HSPB2-C11orf52 H. sapiens SDL Slorth 0.977444 View
ENSG00000166949 SMAD3 ENSG00000168453 HR H. sapiens SDL Slorth 0.977422 View
ENSG00000166949 SMAD3 ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.977417 View
ENSG00000166949 SMAD3 ENSG00000179776 CDH5 H. sapiens SDL Slorth 0.977415 View
ENSG00000156299 TIAM1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977412 View
ENSG00000155465 SLC7A7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977406 View
ENSG00000090273 NUDC ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977356 View