SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000155366 RHOC ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979357 View
ENSG00000166949 SMAD3 ENSG00000176102 CSTF3 H. sapiens SDL Slorth 0.979352 View
ENSG00000166704 ZNF606 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97935 View
ENSG00000019582 CD74 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979342 View
ENSG00000066032 CTNNA2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979334 View
ENSG00000166949 SMAD3 ENSG00000183853 KIRREL H. sapiens SDL Slorth 0.979319 View
ENSG00000163517 HDAC11 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979291 View
ENSG00000075618 FSCN1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979288 View
ENSG00000166947 EPB42 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97928 View
ENSG00000077254 USP33 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979272 View
ENSG00000160145 KALRN ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979261 View
ENSG00000112335 SNX3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979252 View
ENSG00000111540 RAB5B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979248 View
ENSG00000076928 ARHGEF1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979247 View
ENSG00000166949 SMAD3 ENSG00000273841 TAF9 H. sapiens SDL Slorth 0.979234 View
ENSG00000166949 SMAD3 ENSG00000168488 ATXN2L H. sapiens SDL Slorth 0.979228 View
ENSG00000157456 CCNB2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979198 View
ENSG00000133318 RTN3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979198 View
ENSG00000112234 FBXL4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979181 View
ENSG00000166949 SMAD3 ENSG00000197879 MYO1C H. sapiens SDL Slorth 0.979177 View
ENSG00000136750 GAD2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979176 View
ENSG00000113328 CCNG1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979155 View
ENSG00000144134 RABL2A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979151 View
ENSG00000148908 RGS10 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979145 View
ENSG00000115738 ID2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979133 View
ENSG00000166949 SMAD3 ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.979121 View
ENSG00000125084 WNT1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979113 View
ENSG00000072163 LIMS2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97909 View
ENSG00000001626 CFTR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979081 View
ENSG00000095397 WHRN ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979073 View
ENSG00000143847 PPFIA4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979073 View
ENSG00000151746 BICD1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979073 View
ENSG00000166949 SMAD3 ENSG00000198033 TUBA3C H. sapiens SDL Slorth 0.979066 View
ENSG00000163485 ADORA1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979057 View
ENSG00000132386 SERPINF1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979051 View
ENSG00000166949 SMAD3 ENSG00000178562 CD28 H. sapiens SDL Slorth 0.979029 View
ENSG00000100228 RAB36 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979027 View
ENSG00000085185 BCORL1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.979027 View
ENSG00000166949 SMAD3 ENSG00000183161 FANCF H. sapiens SDL Slorth 0.978937 View
ENSG00000118985 ELL2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978921 View