SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000164985 PSIP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980881 View
ENSG00000013441 CLK1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980878 View
ENSG00000166949 SMAD3 ENSG00000167325 RRM1 H. sapiens SDL Slorth 0.980876 View
ENSG00000108984 MAP2K6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980842 View
ENSG00000166949 SMAD3 ENSG00000175793 SFN H. sapiens SDL Slorth 0.98083 View
ENSG00000110148 CCKBR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980804 View
ENSG00000105737 GRIK5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980804 View
ENSG00000166949 SMAD3 ENSG00000178209 PLEC H. sapiens SDL Slorth 0.980776 View
ENSG00000076984 MAP2K7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980774 View
ENSG00000101134 DOK5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980763 View
ENSG00000159496 RGL4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980749 View
ENSG00000166949 SMAD3 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.980736 View
ENSG00000166949 SMAD3 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.980733 View
ENSG00000166949 SMAD3 ENSG00000248333 CDK11B H. sapiens SDL Slorth 0.980731 View
ENSG00000166949 SMAD3 ENSG00000204842 ATXN2 H. sapiens SDL Slorth 0.980719 View
ENSG00000125810 CD93 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980664 View
ENSG00000143420 ENSA ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980656 View
ENSG00000139154 AEBP2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980653 View
ENSG00000166949 SMAD3 ENSG00000205339 IPO7 H. sapiens SDL Slorth 0.980622 View
ENSG00000166949 SMAD3 ENSG00000177426 TGIF1 H. sapiens SDL Slorth 0.980607 View
ENSG00000153561 RMND5A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980584 View
ENSG00000083290 ULK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980577 View
ENSG00000166949 SMAD3 ENSG00000183814 LIN9 H. sapiens SDL Slorth 0.980575 View
ENSG00000166949 SMAD3 ENSG00000213079 SCAF8 H. sapiens SDL Slorth 0.980554 View
ENSG00000166949 SMAD3 ENSG00000167553 TUBA1C H. sapiens SDL Slorth 0.980546 View
ENSG00000117676 RPS6KA1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980518 View
ENSG00000130766 SESN2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980491 View
ENSG00000166949 SMAD3 ENSG00000196914 ARHGEF12 H. sapiens SDL Slorth 0.980478 View
ENSG00000078114 NEBL ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980425 View
ENSG00000108830 RND2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980414 View
ENSG00000166949 SMAD3 ENSG00000167815 PRDX2 H. sapiens SDL Slorth 0.980409 View
ENSG00000117400 MPL ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980385 View
ENSG00000166949 SMAD3 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.980303 View
ENSG00000115221 ITGB6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980255 View
ENSG00000164284 GRPEL2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98025 View
ENSG00000166949 SMAD3 ENSG00000175793 SFN H. sapiens SSL Slorth 0.980243 View
ENSG00000105993 DNAJB6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980237 View
ENSG00000166949 SMAD3 ENSG00000174672 BRSK2 H. sapiens SDL Slorth 0.98022 View
ENSG00000119403 PHF19 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98009 View
ENSG00000154310 TNIK ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.980081 View