SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000166949 SMAD3 ENSG00000173020 GRK2 H. sapiens SDL Slorth 0.978906 View
ENSG00000164867 NOS3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978901 View
ENSG00000165832 TRUB1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.9789 View
ENSG00000125503 PPP1R12C ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97889 View
ENSG00000139998 RAB15 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978864 View
ENSG00000005882 PDK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978864 View
ENSG00000061918 GUCY1B3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978864 View
ENSG00000125740 FOSB ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978847 View
ENSG00000166949 SMAD3 ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.978839 View
ENSG00000166949 SMAD3 ENSG00000177565 TBL1XR1 H. sapiens SDL Slorth 0.97883 View
ENSG00000150995 ITPR1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978796 View
ENSG00000166949 SMAD3 ENSG00000172175 MALT1 H. sapiens SDL Slorth 0.978747 View
ENSG00000166949 SMAD3 ENSG00000198258 UBL5 H. sapiens SDL Slorth 0.978723 View
ENSG00000166949 SMAD3 ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.978714 View
ENSG00000072415 MPP5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978714 View
ENSG00000153922 CHD1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97871 View
ENSG00000067141 NEO1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97871 View
ENSG00000111262 KCNA1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97871 View
ENSG00000112367 FIG4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978697 View
ENSG00000143549 TPM3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978693 View
ENSG00000165699 TSC1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97863 View
ENSG00000143033 MTF2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978609 View
ENSG00000138592 USP8 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978595 View
ENSG00000166949 SMAD3 ENSG00000185811 IKZF1 H. sapiens SDL Slorth 0.978581 View
ENSG00000138594 TMOD3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978571 View
ENSG00000153132 CLGN ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978571 View
ENSG00000110031 LPXN ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978518 View
ENSG00000138613 APH1B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978498 View
ENSG00000124198 ARFGEF2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978487 View
ENSG00000166949 SMAD3 ENSG00000205250 E2F4 H. sapiens SDL Slorth 0.978472 View
ENSG00000140575 IQGAP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978461 View
ENSG00000160193 WDR4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978453 View
ENSG00000166949 SMAD3 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.978447 View
ENSG00000092841 MYL6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978436 View
ENSG00000160007 ARHGAP35 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978434 View
ENSG00000125967 NECAB3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978404 View
ENSG00000135312 HTR1B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978404 View
ENSG00000140750 ARHGAP17 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978404 View
ENSG00000072315 TRPC5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978404 View
ENSG00000107862 GBF1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978361 View