SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000138668 HNRNPD ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.788801 View
ENSG00000149269 PAK1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.788468 View
ENSG00000085733 CTTN ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.788322 View
ENSG00000116473 RAP1A ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.787786 View
ENSG00000112578 BYSL ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.784934 View
ENSG00000166949 SMAD3 ENSG00000215305 VPS16 H. sapiens SSL Slorth 0.784586 View
ENSG00000116016 EPAS1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.784576 View
ENSG00000164362 TERT ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.784519 View
ENSG00000166949 SMAD3 ENSG00000169100 SLC25A6 H. sapiens SSL Slorth 0.783715 View
ENSG00000116288 PARK7 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.78334 View
ENSG00000166949 SMAD3 ENSG00000182541 LIMK2 H. sapiens SSL Slorth 0.783068 View
ENSG00000166949 SMAD3 ENSG00000240344 PPIL3 H. sapiens SSL Slorth 0.782442 View
ENSG00000165527 ARF6 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.781772 View
ENSG00000166949 SMAD3 ENSG00000188739 RBM34 H. sapiens SSL Slorth 0.780873 View
ENSG00000116478 HDAC1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.780811 View
ENSG00000072310 SREBF1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.780769 View
ENSG00000106299 WASL ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.780134 View
ENSG00000164032 H2AFZ ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.779858 View
ENSG00000145715 RASA1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.777771 View
ENSG00000166949 SMAD3 ENSG00000167460 TPM4 H. sapiens SSL Slorth 0.777733 View
ENSG00000132964 CDK8 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.77594 View
ENSG00000050748 MAPK9 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.775325 View
ENSG00000166949 SMAD3 ENSG00000182208 MOB2 H. sapiens SSL Slorth 0.774851 View
ENSG00000166949 SMAD3 ENSG00000173626 TRAPPC3L H. sapiens SSL Slorth 0.774395 View
ENSG00000166888 STAT6 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.773178 View
ENSG00000050820 BCAR1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.773106 View
ENSG00000166949 SMAD3 ENSG00000184076 UQCR10 H. sapiens SSL Slorth 0.772792 View
ENSG00000162236 STX5 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.772783 View
ENSG00000161547 SRSF2 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.77261 View
ENSG00000066468 FGFR2 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.772107 View
ENSG00000144028 SNRNP200 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.769317 View
ENSG00000166949 SMAD3 ENSG00000183943 PRKX H. sapiens SSL Slorth 0.769215 View
ENSG00000166949 SMAD3 ENSG00000198517 MAFK H. sapiens SSL Slorth 0.768641 View
ENSG00000166949 SMAD3 ENSG00000262814 MRPL12 H. sapiens SSL Slorth 0.766838 View
ENSG00000026103 FAS ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.766786 View
ENSG00000166949 SMAD3 ENSG00000168883 USP39 H. sapiens SSL Slorth 0.766781 View
ENSG00000166949 SMAD3 ENSG00000214717 ZBED1 H. sapiens SSL Slorth 0.765943 View
ENSG00000166949 SMAD3 ENSG00000167711 SERPINF2 H. sapiens SSL Slorth 0.765815 View
ENSG00000108840 HDAC5 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.765813 View
ENSG00000166949 SMAD3 ENSG00000174672 BRSK2 H. sapiens SSL Slorth 0.764061 View