SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000160867 FGFR4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98651 View
ENSG00000166949 SMAD3 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.986256 View
ENSG00000166949 SMAD3 ENSG00000172534 HCFC1 H. sapiens SDL Slorth 0.986238 View
ENSG00000166949 SMAD3 ENSG00000186871 ERCC6L H. sapiens SDL Slorth 0.986211 View
ENSG00000166949 SMAD3 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.986042 View
ENSG00000166949 SMAD3 ENSG00000169554 ZEB2 H. sapiens SDL Slorth 0.986002 View
ENSG00000166949 SMAD3 ENSG00000198677 TTC37 H. sapiens SDL Slorth 0.985944 View
ENSG00000166949 SMAD3 ENSG00000171435 KSR2 H. sapiens SDL Slorth 0.985877 View
ENSG00000166949 SMAD3 ENSG00000167552 TUBA1A H. sapiens SDL Slorth 0.98564 View
ENSG00000166949 SMAD3 ENSG00000175197 DDIT3 H. sapiens SDL Slorth 0.985582 View
ENSG00000166949 SMAD3 ENSG00000177084 POLE H. sapiens SDL Slorth 0.985554 View
ENSG00000166949 SMAD3 ENSG00000198286 CARD11 H. sapiens SDL Slorth 0.985475 View
ENSG00000166949 SMAD3 ENSG00000225830 ERCC6 H. sapiens SDL Slorth 0.985336 View
ENSG00000166949 SMAD3 ENSG00000173334 TRIB1 H. sapiens SDL Slorth 0.985247 View
ENSG00000166949 SMAD3 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.985121 View
ENSG00000166949 SMAD3 ENSG00000171824 EXOSC10 H. sapiens SDL Slorth 0.984993 View
ENSG00000164654 MIOS ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98494 View
ENSG00000166949 SMAD3 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.984916 View
ENSG00000166949 SMAD3 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.984907 View
ENSG00000166949 SMAD3 ENSG00000173542 MOB1B H. sapiens SDL Slorth 0.984901 View
ENSG00000100239 PPP6R2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984862 View
ENSG00000080561 MID2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984851 View
ENSG00000104892 KLC3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984841 View
ENSG00000150768 DLAT ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984839 View
ENSG00000067992 PDK3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984839 View
ENSG00000166949 SMAD3 ENSG00000186716 BCR H. sapiens SDL Slorth 0.984825 View
ENSG00000066455 GOLGA5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984824 View
ENSG00000100372 SLC25A17 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984814 View
ENSG00000148248 SURF4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984814 View
ENSG00000130703 OSBPL2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984814 View
ENSG00000086619 ERO1B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984814 View
ENSG00000154997 SEPT14 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984809 View
ENSG00000166797 FAM96A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984804 View
ENSG00000106346 USP42 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984799 View
ENSG00000143801 PSEN2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984797 View
ENSG00000102317 RBM3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98477 View
ENSG00000120500 ARR3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984752 View
ENSG00000135604 STX11 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98472 View
ENSG00000113240 CLK4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98472 View
ENSG00000129354 AP1M2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98472 View