SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000153944 MSI2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98472 View
ENSG00000007908 SELE ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984716 View
ENSG00000109519 GRPEL1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984685 View
ENSG00000166949 SMAD3 ENSG00000177272 KCNA3 H. sapiens SDL Slorth 0.984652 View
ENSG00000166949 SMAD3 ENSG00000171456 ASXL1 H. sapiens SDL Slorth 0.984629 View
ENSG00000110048 OSBP ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984627 View
ENSG00000139668 WDFY2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984573 View
ENSG00000145358 DDIT4L ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984569 View
ENSG00000148730 EIF4EBP2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984551 View
ENSG00000157601 MX1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984463 View
ENSG00000141551 CSNK1D ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984451 View
ENSG00000166949 SMAD3 ENSG00000173801 JUP H. sapiens SDL Slorth 0.984405 View
ENSG00000166949 SMAD3 ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.984394 View
ENSG00000122566 HNRNPA2B1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984375 View
ENSG00000166949 SMAD3 ENSG00000242173 ARHGDIG H. sapiens SDL Slorth 0.984328 View
ENSG00000166949 SMAD3 ENSG00000170004 CHD3 H. sapiens SDL Slorth 0.984322 View
ENSG00000133124 IRS4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984267 View
ENSG00000102996 MMP15 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98425 View
ENSG00000105290 APLP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984246 View
ENSG00000166949 SMAD3 ENSG00000180176 TH H. sapiens SDL Slorth 0.984235 View
ENSG00000160469 BRSK1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984227 View
ENSG00000099785 MARCH2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984218 View
ENSG00000149968 MMP3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984203 View
ENSG00000166949 SMAD3 ENSG00000221829 FANCG H. sapiens SDL Slorth 0.984183 View
ENSG00000128731 HERC2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984172 View
ENSG00000136014 USP44 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984153 View
ENSG00000166949 SMAD3 ENSG00000183955 KMT5A H. sapiens SDL Slorth 0.984146 View
ENSG00000116574 RHOU ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984136 View
ENSG00000079335 CDC14A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984134 View
ENSG00000166949 SMAD3 ENSG00000198373 WWP2 H. sapiens SDL Slorth 0.984052 View
ENSG00000106799 TGFBR1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984048 View
ENSG00000166949 SMAD3 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.984024 View
ENSG00000007264 MATK ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.984022 View
ENSG00000079156 OSBPL6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.983947 View
ENSG00000152822 GRM1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.983947 View
ENSG00000077380 DYNC1I2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.983947 View
ENSG00000021574 SPAST ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.983947 View
ENSG00000102683 SGCG ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.983947 View
ENSG00000166949 SMAD3 ENSG00000173110 HSPA6 H. sapiens SDL Slorth 0.983918 View
ENSG00000137673 MMP7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.98387 View