SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000152104 PTPN14 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977336 View
ENSG00000083857 FAT1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977332 View
ENSG00000163536 SERPINI1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97733 View
ENSG00000115616 SLC9A2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977329 View
ENSG00000166949 SMAD3 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.977281 View
ENSG00000064393 HIPK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977247 View
ENSG00000134058 CDK7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977214 View
ENSG00000103966 EHD4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977196 View
ENSG00000166949 SMAD3 ENSG00000255112 CHMP1B H. sapiens SDL Slorth 0.977185 View
ENSG00000164402 SEPT8 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977178 View
ENSG00000148484 RSU1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977178 View
ENSG00000143473 KCNH1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977149 View
ENSG00000166949 SMAD3 ENSG00000183337 BCOR H. sapiens SDL Slorth 0.977144 View
ENSG00000162512 SDC3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97714 View
ENSG00000164919 COX6C ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97714 View
ENSG00000143867 OSR1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977135 View
ENSG00000166949 SMAD3 ENSG00000253729 PRKDC H. sapiens SDL Slorth 0.977074 View
ENSG00000166949 SMAD3 ENSG00000198793 MTOR H. sapiens SDL Slorth 0.977073 View
ENSG00000139318 DUSP6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977063 View
ENSG00000087274 ADD1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977031 View
ENSG00000133112 TPT1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977027 View
ENSG00000115677 HDLBP ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97702 View
ENSG00000118508 RAB32 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977019 View
ENSG00000137942 FNBP1L ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97701 View
ENSG00000148200 NR6A1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976984 View
ENSG00000166949 SMAD3 ENSG00000171960 PPIH H. sapiens SSL Slorth 0.976951 View
ENSG00000166949 SMAD3 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.976949 View
ENSG00000162775 RBM15 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976937 View
ENSG00000136273 HUS1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976898 View
ENSG00000130751 NPAS1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976873 View
ENSG00000115317 HTRA2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976873 View
ENSG00000008196 TFAP2B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976858 View
ENSG00000080371 RAB21 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976835 View
ENSG00000104140 RHOV ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976834 View
ENSG00000116641 DOCK7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976824 View
ENSG00000157514 TSC22D3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976805 View
ENSG00000166949 SMAD3 ENSG00000198648 STK39 H. sapiens SDL Slorth 0.976795 View
ENSG00000166949 SMAD3 ENSG00000168209 DDIT4 H. sapiens SDL Slorth 0.97675 View
ENSG00000117650 NEK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976747 View
ENSG00000166949 SMAD3 ENSG00000171241 SHCBP1 H. sapiens SDL Slorth 0.976739 View