SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000090621 PABPC4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975543 View
ENSG00000122779 TRIM24 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97554 View
ENSG00000133835 HSD17B4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97553 View
ENSG00000166949 SMAD3 ENSG00000198176 TFDP1 H. sapiens SDL Slorth 0.975515 View
ENSG00000070159 PTPN3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975505 View
ENSG00000166949 SMAD3 ENSG00000213465 ARL2 H. sapiens SDL Slorth 0.975504 View
ENSG00000166228 PCBD1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.9755 View
ENSG00000143556 S100A7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975483 View
ENSG00000117625 RCOR3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975481 View
ENSG00000166949 SMAD3 ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.975467 View
ENSG00000148584 A1CF ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975462 View
ENSG00000147130 ZMYM3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975458 View
ENSG00000074181 NOTCH3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975452 View
ENSG00000166949 SMAD3 ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.97542 View
ENSG00000072062 PRKACA ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975349 View
ENSG00000066777 ARFGEF1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975342 View
ENSG00000166949 SMAD3 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.975337 View
ENSG00000132356 PRKAA1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975327 View
ENSG00000164077 MON1A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975313 View
ENSG00000011454 RABGAP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975301 View
ENSG00000166949 SMAD3 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.975289 View
ENSG00000166949 SMAD3 ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.975253 View
ENSG00000166949 SMAD3 ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.975228 View
ENSG00000124145 SDC4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975224 View
ENSG00000166949 SMAD3 ENSG00000184260 HIST2H2AC H. sapiens SSL Slorth 0.975219 View
ENSG00000095787 WAC ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975189 View
ENSG00000011132 APBA3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975187 View
ENSG00000166949 SMAD3 ENSG00000169967 MAP3K2 H. sapiens SSL Slorth 0.975185 View
ENSG00000072736 NFATC3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975168 View
ENSG00000134686 PHC2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975164 View
ENSG00000166949 SMAD3 ENSG00000187735 TCEA1 H. sapiens SSL Slorth 0.975155 View
ENSG00000070444 MNT ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975126 View
ENSG00000166949 SMAD3 ENSG00000168439 STIP1 H. sapiens SDL Slorth 0.975121 View
ENSG00000115884 SDC1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97512 View
ENSG00000166949 SMAD3 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.975106 View
ENSG00000166949 SMAD3 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.975089 View
ENSG00000100092 SH3BP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975073 View
ENSG00000166949 SMAD3 ENSG00000175305 CCNE2 H. sapiens SDL Slorth 0.975035 View
ENSG00000105329 TGFB1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.975022 View
ENSG00000166949 SMAD3 ENSG00000198887 SMC5 H. sapiens SDL Slorth 0.974992 View