SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000103496 STX4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976739 View
ENSG00000166949 SMAD3 ENSG00000198625 MDM4 H. sapiens SDL Slorth 0.976664 View
ENSG00000079785 DDX1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976635 View
ENSG00000107929 LARP4B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976586 View
ENSG00000117984 CTSD ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976577 View
ENSG00000166949 SMAD3 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.976564 View
ENSG00000166949 SMAD3 ENSG00000170385 SLC30A1 H. sapiens SDL Slorth 0.976563 View
ENSG00000166949 SMAD3 ENSG00000198218 QRICH1 H. sapiens SDL Slorth 0.976563 View
ENSG00000146232 NFKBIE ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976561 View
ENSG00000166949 SMAD3 ENSG00000175029 CTBP2 H. sapiens SDL Slorth 0.976557 View
ENSG00000143294 PRCC ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976529 View
ENSG00000166949 SMAD3 ENSG00000183856 IQGAP3 H. sapiens SDL Slorth 0.976521 View
ENSG00000142945 KIF2C ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976521 View
ENSG00000166949 SMAD3 ENSG00000170734 POLH H. sapiens SSL Slorth 0.976515 View
ENSG00000070882 OSBPL3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976511 View
ENSG00000159200 RCAN1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976511 View
ENSG00000112246 SIM1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976501 View
ENSG00000159263 SIM2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976501 View
ENSG00000141522 ARHGDIA ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976494 View
ENSG00000161940 BCL6B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976489 View
ENSG00000135966 TGFBRAP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976475 View
ENSG00000130669 PAK4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976475 View
ENSG00000139797 RNF113B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97647 View
ENSG00000166949 SMAD3 ENSG00000175216 CKAP5 H. sapiens SDL Slorth 0.976465 View
ENSG00000163435 ELF3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976447 View
ENSG00000133056 PIK3C2B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976441 View
ENSG00000166224 SGPL1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976423 View
ENSG00000166949 SMAD3 ENSG00000198586 TLK1 H. sapiens SDL Slorth 0.976411 View
ENSG00000116604 MEF2D ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976398 View
ENSG00000100417 PMM1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976378 View
ENSG00000166949 SMAD3 ENSG00000169016 E2F6 H. sapiens SDL Slorth 0.976293 View
ENSG00000138160 KIF11 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97629 View
ENSG00000047849 MAP4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97629 View
ENSG00000145331 TRMT10A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976277 View
ENSG00000166949 SMAD3 ENSG00000187735 TCEA1 H. sapiens SDL Slorth 0.976277 View
ENSG00000166949 SMAD3 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.976276 View
ENSG00000089685 BIRC5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976273 View
ENSG00000115020 PIKFYVE ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.976217 View
ENSG00000166949 SMAD3 ENSG00000173207 CKS1B H. sapiens SDL Slorth 0.976214 View
ENSG00000166949 SMAD3 ENSG00000187239 FNBP1 H. sapiens SDL Slorth 0.976176 View