SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000166949 SMAD3 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.978343 View
ENSG00000147010 SH3KBP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978323 View
ENSG00000105204 DYRK1B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978312 View
ENSG00000110880 CORO1C ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978296 View
ENSG00000166949 SMAD3 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.97829 View
ENSG00000126583 PRKCG ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978283 View
ENSG00000166949 SMAD3 ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.978279 View
ENSG00000165125 TRPV6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978274 View
ENSG00000166949 SMAD3 ENSG00000167004 PDIA3 H. sapiens SDL Slorth 0.978257 View
ENSG00000072134 EPN2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978242 View
ENSG00000166949 SMAD3 ENSG00000183684 ALYREF H. sapiens SDL Slorth 0.978242 View
ENSG00000166949 SMAD3 ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.978207 View
ENSG00000124782 RREB1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978194 View
ENSG00000099365 STX1B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978192 View
ENSG00000166949 SMAD3 ENSG00000175745 NR2F1 H. sapiens SDL Slorth 0.978181 View
ENSG00000114554 PLXNA1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978176 View
ENSG00000165238 WNK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978176 View
ENSG00000166949 SMAD3 ENSG00000177733 HNRNPA0 H. sapiens SDL Slorth 0.978129 View
ENSG00000166949 SMAD3 ENSG00000170004 CHD3 H. sapiens SSL Slorth 0.978092 View
ENSG00000108924 HLF ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978091 View
ENSG00000115685 PPP1R7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978085 View
ENSG00000122966 CIT ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978049 View
ENSG00000125107 CNOT1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978046 View
ENSG00000166949 SMAD3 ENSG00000168959 GRM5 H. sapiens SDL Slorth 0.978042 View
ENSG00000118971 CCND2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.978021 View
ENSG00000146457 WTAP ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977995 View
ENSG00000105287 PRKD2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977988 View
ENSG00000166949 SMAD3 ENSG00000198909 MAP3K3 H. sapiens SSL Slorth 0.977979 View
ENSG00000140983 RHOT2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977972 View
ENSG00000166949 SMAD3 ENSG00000185236 RAB11B H. sapiens SDL Slorth 0.977962 View
ENSG00000157087 ATP2B2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977943 View
ENSG00000166949 SMAD3 ENSG00000169100 SLC25A6 H. sapiens SDL Slorth 0.97793 View
ENSG00000166949 SMAD3 ENSG00000169696 ASPSCR1 H. sapiens SDL Slorth 0.977848 View
ENSG00000166949 SMAD3 ENSG00000167996 FTH1 H. sapiens SDL Slorth 0.977844 View
ENSG00000081377 CDC14B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97784 View
ENSG00000058404 CAMK2B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977829 View
ENSG00000113758 DBN1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977813 View
ENSG00000166949 SMAD3 ENSG00000177189 RPS6KA3 H. sapiens SDL Slorth 0.977812 View
ENSG00000163394 CCKAR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977811 View
ENSG00000140199 SLC12A6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977811 View