BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101557 USP14 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.809454 View
ENSG00000155438 NIFK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.809322 View
ENSG00000139343 SNRPF ENSG00000157764 BRAF H. sapiens SSL Slorth 0.809177 View
ENSG00000157764 BRAF ENSG00000169696 ASPSCR1 H. sapiens SSL Slorth 0.808969 View
ENSG00000079805 DNM2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.80894 View
ENSG00000157764 BRAF ENSG00000170776 AKAP13 H. sapiens SSL Slorth 0.808805 View
ENSG00000115946 PNO1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.808739 View
ENSG00000157764 BRAF ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.80871 View
ENSG00000157764 BRAF ENSG00000168646 AXIN2 H. sapiens SSL Slorth 0.808693 View
ENSG00000157764 BRAF ENSG00000164171 ITGA2 H. sapiens SSL Slorth 0.80845 View
ENSG00000155827 RNF20 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.808365 View
ENSG00000157764 BRAF ENSG00000159210 SNF8 H. sapiens SSL Slorth 0.808262 View
ENSG00000157764 BRAF ENSG00000198612 COPS8 H. sapiens SSL Slorth 0.80819 View
ENSG00000157764 BRAF ENSG00000187446 CHP1 H. sapiens SSL Slorth 0.808067 View
ENSG00000157764 BRAF ENSG00000175334 BANF1 H. sapiens SSL Slorth 0.807866 View
ENSG00000157764 BRAF ENSG00000173207 CKS1B H. sapiens SSL Slorth 0.807721 View
ENSG00000102554 KLF5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.807673 View
ENSG00000115524 SF3B1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.807575 View
ENSG00000121989 ACVR2A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.807272 View
ENSG00000157764 BRAF ENSG00000158022 TRIM63 H. sapiens SSL Slorth 0.807129 View
ENSG00000107263 RAPGEF1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.80686 View
ENSG00000105968 H2AFV ENSG00000157764 BRAF H. sapiens SSL Slorth 0.806783 View
ENSG00000115677 HDLBP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.806656 View
ENSG00000157764 BRAF ENSG00000177666 PNPLA2 H. sapiens SSL Slorth 0.806552 View
ENSG00000157764 BRAF ENSG00000173542 MOB1B H. sapiens SSL Slorth 0.806416 View
ENSG00000145555 MYO10 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.806167 View
ENSG00000105723 GSK3A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.805786 View
ENSG00000157764 BRAF ENSG00000164327 RICTOR H. sapiens SSL Slorth 0.805497 View
ENSG00000157764 BRAF ENSG00000178209 PLEC H. sapiens SSL Slorth 0.80541 View
ENSG00000157764 BRAF ENSG00000161270 NPHS1 H. sapiens SSL Slorth 0.805329 View
ENSG00000157764 BRAF ENSG00000167136 ENDOG H. sapiens SSL Slorth 0.80523 View
ENSG00000103510 KAT8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.805186 View
ENSG00000128340 RAC2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.805173 View
ENSG00000157764 BRAF ENSG00000198033 TUBA3C H. sapiens SSL Slorth 0.805119 View
ENSG00000121152 NCAPH ENSG00000157764 BRAF H. sapiens SSL Slorth 0.804763 View
ENSG00000113300 CNOT6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.80455 View
ENSG00000157764 BRAF ENSG00000160867 FGFR4 H. sapiens SSL Slorth 0.804434 View
ENSG00000122367 LDB3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.804021 View
ENSG00000109805 NCAPG ENSG00000157764 BRAF H. sapiens SSL Slorth 0.803778 View
ENSG00000136854 STXBP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.803568 View