BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000107201 DDX58 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.803374 View
ENSG00000157764 BRAF ENSG00000184675 AMER1 H. sapiens SSL Slorth 0.803065 View
ENSG00000157764 BRAF ENSG00000172315 TP53RK H. sapiens SSL Slorth 0.802985 View
ENSG00000151067 CACNA1C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.80273 View
ENSG00000105329 TGFB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.802374 View
ENSG00000149100 EIF3M ENSG00000157764 BRAF H. sapiens SSL Slorth 0.802224 View
ENSG00000157764 BRAF ENSG00000188191 PRKAR1B H. sapiens SSL Slorth 0.802203 View
ENSG00000122218 COPA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.802075 View
ENSG00000157764 BRAF ENSG00000172409 CLP1 H. sapiens SSL Slorth 0.80187 View
ENSG00000157764 BRAF ENSG00000181090 EHMT1 H. sapiens SSL Slorth 0.801531 View
ENSG00000141551 CSNK1D ENSG00000157764 BRAF H. sapiens SSL Slorth 0.80152 View
ENSG00000134759 ELP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.801408 View
ENSG00000100401 RANGAP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.801034 View
ENSG00000157764 BRAF ENSG00000213066 FGFR1OP H. sapiens SSL Slorth 0.800275 View
ENSG00000109118 PHF12 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.800121 View
ENSG00000157764 BRAF ENSG00000178562 CD28 H. sapiens SSL Slorth 0.800117 View
ENSG00000134597 RBMX2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.800061 View
ENSG00000129993 CBFA2T3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.799974 View
ENSG00000124788 ATXN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.799861 View
ENSG00000052802 MSMO1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.799461 View
ENSG00000117461 PIK3R3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.799418 View
ENSG00000127564 PKMYT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.799302 View
ENSG00000114739 ACVR2B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.799206 View
ENSG00000101361 NOP56 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.798992 View
ENSG00000086758 HUWE1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.798946 View
ENSG00000106803 SEC61B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.7989 View
ENSG00000157764 BRAF ENSG00000183943 PRKX H. sapiens SSL Slorth 0.798723 View
ENSG00000003436 TFPI ENSG00000157764 BRAF H. sapiens SSL Slorth 0.798643 View
ENSG00000157764 BRAF ENSG00000161800 RACGAP1 H. sapiens SSL Slorth 0.798536 View
ENSG00000117528 ABCD3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.798533 View
ENSG00000157764 BRAF ENSG00000173334 TRIB1 H. sapiens SSL Slorth 0.798282 View
ENSG00000082781 ITGB5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.798188 View
ENSG00000071539 TRIP13 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.797748 View
ENSG00000157764 BRAF ENSG00000198890 PRMT6 H. sapiens SSL Slorth 0.797617 View
ENSG00000119318 RAD23B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.797469 View
ENSG00000157764 BRAF ENSG00000166869 CHP2 H. sapiens SSL Slorth 0.797343 View
ENSG00000146963 LUC7L2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.797191 View
ENSG00000157764 BRAF ENSG00000167553 TUBA1C H. sapiens SSL Slorth 0.796838 View
ENSG00000276618 RAD17 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.796575 View
ENSG00000066654 THUMPD1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.796222 View