PHF12 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PHF12	ENSG00000109118	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription corepressor activity transcription corepressor binding chromatin binding protein binding zinc ion binding phosphatidylinositol binding histone binding	RCO1 (S. cerevisiae) CG3815 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)