BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000182149 IST1 H. sapiens SSL Slorth 0.816665 View
ENSG00000157764 BRAF ENSG00000182504 CEP97 H. sapiens SSL Slorth 0.816473 View
ENSG00000115866 DARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.816252 View
ENSG00000157764 BRAF ENSG00000163399 ATP1A1 H. sapiens SSL Slorth 0.816158 View
ENSG00000142168 SOD1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.816062 View
ENSG00000120705 ETF1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.815887 View
ENSG00000115286 NDUFS7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.815447 View
ENSG00000153201 RANBP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.815395 View
ENSG00000090861 AARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.815379 View
ENSG00000106993 CDC37L1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.815153 View
ENSG00000091140 DLD ENSG00000157764 BRAF H. sapiens SSL Slorth 0.814809 View
ENSG00000157764 BRAF ENSG00000241553 ARPC4 H. sapiens SSL Slorth 0.814616 View
ENSG00000101751 POLI ENSG00000157764 BRAF H. sapiens SSL Slorth 0.814167 View
ENSG00000157764 BRAF ENSG00000239672 NME1 H. sapiens SSL Slorth 0.814119 View
ENSG00000151923 TIAL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.813991 View
ENSG00000130024 PHF10 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.81376 View
ENSG00000112081 SRSF3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.813715 View
ENSG00000157764 BRAF ENSG00000163636 PSMD6 H. sapiens SSL Slorth 0.813453 View
ENSG00000138685 FGF2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.813333 View
ENSG00000157764 BRAF ENSG00000244405 ETV5 H. sapiens SSL Slorth 0.813181 View
ENSG00000157764 BRAF ENSG00000171497 PPID H. sapiens SSL Slorth 0.812913 View
ENSG00000138346 DNA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.812825 View
ENSG00000157764 BRAF ENSG00000174371 EXO1 H. sapiens SSL Slorth 0.812808 View
ENSG00000084234 APLP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.812727 View
ENSG00000125630 POLR1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.812278 View
ENSG00000147050 KDM6A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.812016 View
ENSG00000122728 TAF1L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.811744 View
ENSG00000135100 HNF1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.811615 View
ENSG00000157764 BRAF ENSG00000172602 RND1 H. sapiens SSL Slorth 0.81154 View
ENSG00000116141 MARK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.81152 View
ENSG00000136279 DBNL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.81149 View
ENSG00000157764 BRAF ENSG00000165672 PRDX3 H. sapiens SSL Slorth 0.811373 View
ENSG00000100722 ZC3H14 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.811311 View
ENSG00000157764 BRAF ENSG00000255112 CHMP1B H. sapiens SSL Slorth 0.811074 View
ENSG00000122958 VPS26A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.810867 View
ENSG00000157764 BRAF ENSG00000184216 IRAK1 H. sapiens SSL Slorth 0.810686 View
ENSG00000157764 BRAF ENSG00000173848 NET1 H. sapiens SSL Slorth 0.810003 View
ENSG00000116489 CAPZA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.809643 View
ENSG00000137267 TUBB2A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.809595 View
ENSG00000152086 TUBA3E ENSG00000157764 BRAF H. sapiens SSL Slorth 0.809513 View