BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000160293 VAV2 H. sapiens SSL Slorth 0.84285 View
ENSG00000114573 ATP6V1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.842833 View
ENSG00000154767 XPC ENSG00000157764 BRAF H. sapiens SSL Slorth 0.842663 View
ENSG00000157764 BRAF ENSG00000196218 RYR1 H. sapiens SSL Slorth 0.842597 View
ENSG00000142230 SAE1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.842291 View
ENSG00000135829 DHX9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.842171 View
ENSG00000152795 HNRNPDL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.841214 View
ENSG00000157764 BRAF ENSG00000171848 RRM2 H. sapiens SSL Slorth 0.841106 View
ENSG00000131828 PDHA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.841076 View
ENSG00000154719 MRPL39 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.841053 View
ENSG00000157764 BRAF ENSG00000167670 CHAF1A H. sapiens SSL Slorth 0.840934 View
ENSG00000058262 SEC61A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.840507 View
ENSG00000157764 BRAF ENSG00000172175 MALT1 H. sapiens SSL Slorth 0.840377 View
ENSG00000157764 BRAF ENSG00000185344 ATP6V0A2 H. sapiens SSL Slorth 0.840177 View
ENSG00000157764 BRAF ENSG00000182247 UBE2E2 H. sapiens SSL Slorth 0.840163 View
ENSG00000063245 EPN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.840002 View
ENSG00000121892 PDS5A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.839938 View
ENSG00000142875 PRKACB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.839568 View
ENSG00000157764 BRAF ENSG00000169174 PCSK9 H. sapiens SSL Slorth 0.839442 View
ENSG00000120738 EGR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.839434 View
ENSG00000100297 MCM5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.839119 View
ENSG00000157764 BRAF ENSG00000196459 TRAPPC2 H. sapiens SSL Slorth 0.839015 View
ENSG00000136504 KAT7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.838942 View
ENSG00000118007 STAG1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.838823 View
ENSG00000004975 DVL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.838814 View
ENSG00000157764 BRAF ENSG00000183072 NKX2-5 H. sapiens SSL Slorth 0.838787 View
ENSG00000157764 BRAF ENSG00000198959 TGM2 H. sapiens SSL Slorth 0.838785 View
ENSG00000095002 MSH2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.838675 View
ENSG00000100201 DDX17 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.838399 View
ENSG00000157764 BRAF ENSG00000205339 IPO7 H. sapiens SSL Slorth 0.83831 View
ENSG00000157764 BRAF ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.838113 View
ENSG00000126458 RRAS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.838031 View
ENSG00000119414 PPP6C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.83799 View
ENSG00000157764 BRAF ENSG00000163960 UBXN7 H. sapiens SSL Slorth 0.837979 View
ENSG00000157764 BRAF ENSG00000185811 IKZF1 H. sapiens SSL Slorth 0.837816 View
ENSG00000138696 BMPR1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.837814 View
ENSG00000157764 BRAF ENSG00000160469 BRSK1 H. sapiens SSL Slorth 0.8378 View
ENSG00000157764 BRAF ENSG00000183495 EP400 H. sapiens SSL Slorth 0.837616 View
ENSG00000157764 BRAF ENSG00000166347 CYB5A H. sapiens SSL Slorth 0.837318 View
ENSG00000092853 CLSPN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.837208 View