BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000160201 U2AF1 H. sapiens SSL Slorth 0.853859 View
ENSG00000113615 SEC24A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.853652 View
ENSG00000124207 CSE1L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.853593 View
ENSG00000157764 BRAF ENSG00000158169 FANCC H. sapiens SSL Slorth 0.853502 View
ENSG00000069399 BCL3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.852888 View
ENSG00000157764 BRAF ENSG00000175592 FOSL1 H. sapiens SSL Slorth 0.852653 View
ENSG00000157764 BRAF ENSG00000169679 BUB1 H. sapiens SSL Slorth 0.852249 View
ENSG00000007255 TRAPPC6A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.852141 View
ENSG00000100280 AP1B1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.851739 View
ENSG00000157764 BRAF ENSG00000205302 SNX2 H. sapiens SSL Slorth 0.851645 View
ENSG00000157764 BRAF ENSG00000186153 WWOX H. sapiens SSL Slorth 0.85157 View
ENSG00000139112 GABARAPL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.850771 View
ENSG00000130429 ARPC1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.850441 View
ENSG00000157764 BRAF ENSG00000196396 PTPN1 H. sapiens SSL Slorth 0.850288 View
ENSG00000013503 POLR3B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.849857 View
ENSG00000157764 BRAF ENSG00000176102 CSTF3 H. sapiens SSL Slorth 0.84945 View
ENSG00000106976 DNM1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.849423 View
ENSG00000132388 UBE2G1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.849084 View
ENSG00000157764 BRAF ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.849071 View
ENSG00000147669 POLR2K ENSG00000157764 BRAF H. sapiens SSL Slorth 0.849047 View
ENSG00000136986 DERL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.848946 View
ENSG00000115053 NCL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.8485 View
ENSG00000134250 NOTCH2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.848328 View
ENSG00000137822 TUBGCP4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.848279 View
ENSG00000157764 BRAF ENSG00000198356 ASNA1 H. sapiens SSL Slorth 0.847799 View
ENSG00000157764 BRAF ENSG00000196839 ADA H. sapiens SSL Slorth 0.847509 View
ENSG00000157764 BRAF ENSG00000166855 CLPX H. sapiens SSL Slorth 0.847142 View
ENSG00000157764 BRAF ENSG00000169100 SLC25A6 H. sapiens SSL Slorth 0.846683 View
ENSG00000157764 BRAF ENSG00000169710 FASN H. sapiens SSL Slorth 0.846083 View
ENSG00000140416 TPM1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.845985 View
ENSG00000157764 BRAF ENSG00000254505 CHMP4A H. sapiens SSL Slorth 0.845014 View
ENSG00000122566 HNRNPA2B1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.844926 View
ENSG00000091009 RBM27 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.844835 View
ENSG00000101161 PRPF6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.844652 View
ENSG00000157764 BRAF ENSG00000168385 SEPT2 H. sapiens SSL Slorth 0.844552 View
ENSG00000157764 BRAF ENSG00000163577 EIF5A2 H. sapiens SSL Slorth 0.844261 View
ENSG00000157764 BRAF ENSG00000173540 GMPPB H. sapiens SSL Slorth 0.844253 View
ENSG00000157764 BRAF ENSG00000167996 FTH1 H. sapiens SSL Slorth 0.844215 View
ENSG00000079950 STX7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.844106 View
ENSG00000113810 SMC4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.843623 View