BRAF - FASN

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
FASN	ENSG00000169710	No diseases in record	ORLISTAT	fatty acid synthase activity [acyl-carrier-protein] S-acetyltransferase activity [acyl-carrier-protein] S-malonyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity oleoyl-[acyl-carrier-protein] hydrolase activity protein binding drug binding myristoyl-[acyl-carrier-protein] hydrolase activity palmitoyl-[acyl-carrier-protein] hydrolase activity phosphopantetheine binding protein homodimerization activity enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity NADPH binding cadherin binding involved in cell-cell adhesion 3-oxo-pimeloyl-[acp] methyl ester reductase activity	CEM1 (S. cerevisiae)