BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000028528 SNX1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.883061 View
ENSG00000157764 BRAF ENSG00000273841 TAF9 H. sapiens SSL Slorth 0.882822 View
ENSG00000139842 CUL4A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.882397 View
ENSG00000117360 PRPF3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.882133 View
ENSG00000155097 ATP6V1C1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.882011 View
ENSG00000104885 DOT1L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.881951 View
ENSG00000157764 BRAF ENSG00000166333 ILK H. sapiens SSL Slorth 0.881706 View
ENSG00000145375 SPATA5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.881591 View
ENSG00000141552 ANAPC11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.881521 View
ENSG00000144231 POLR2D ENSG00000157764 BRAF H. sapiens SSL Slorth 0.881289 View
ENSG00000066027 PPP2R5A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.881145 View
ENSG00000103496 STX4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.88106 View
ENSG00000147684 NDUFB9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.881003 View
ENSG00000017797 RALBP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880995 View
ENSG00000077063 CTTNBP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880967 View
ENSG00000109062 SLC9A3R1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880887 View
ENSG00000157764 BRAF ENSG00000165458 INPPL1 H. sapiens SSL Slorth 0.880813 View
ENSG00000111581 NUP107 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880639 View
ENSG00000157764 BRAF ENSG00000163041 H3F3A H. sapiens SSL Slorth 0.880585 View
ENSG00000111596 CNOT2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880416 View
ENSG00000143093 STRIP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880333 View
ENSG00000106089 STX1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880244 View
ENSG00000112715 VEGFA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.880183 View
ENSG00000157764 BRAF ENSG00000179091 CYC1 H. sapiens SSL Slorth 0.880092 View
ENSG00000157764 BRAF ENSG00000164032 H2AFZ H. sapiens SSL Slorth 0.880022 View
ENSG00000085978 ATG16L1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.879785 View
ENSG00000004660 CAMKK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.879775 View
ENSG00000157764 BRAF ENSG00000198677 TTC37 H. sapiens SSL Slorth 0.879644 View
ENSG00000124171 PARD6B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.879329 View
ENSG00000157764 BRAF ENSG00000171723 GPHN H. sapiens SSL Slorth 0.879295 View
ENSG00000157764 BRAF ENSG00000167815 PRDX2 H. sapiens SSL Slorth 0.878834 View
ENSG00000034713 GABARAPL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.878574 View
ENSG00000088986 DYNLL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.878216 View
ENSG00000157020 SEC13 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.877842 View
ENSG00000117133 RPF1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.877827 View
ENSG00000078061 ARAF ENSG00000157764 BRAF H. sapiens SSL Slorth 0.87775 View
ENSG00000143437 ARNT ENSG00000157764 BRAF H. sapiens SSL Slorth 0.877534 View
ENSG00000126216 TUBGCP3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.877379 View
ENSG00000085733 CTTN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.877102 View
ENSG00000152256 PDK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.87694 View