ARAF - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARAF	ENSG00000078061	cholangiocarcinoma lung adenocarcinoma Langerhans cell histiocytosis	No drugs in record	protein kinase activity protein serine/threonine kinase activity signal transducer activity, downstream of receptor protein binding ATP binding metal ion binding	lin-45 (C. elegans)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)