BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000173674 EIF1AX H. sapiens SSL Slorth 0.898028 View
ENSG00000150995 ITPR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.897964 View
ENSG00000115091 ACTR3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.897741 View
ENSG00000119487 MAPKAP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.89765 View
ENSG00000126215 XRCC3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.89762 View
ENSG00000157764 BRAF ENSG00000159259 CHAF1B H. sapiens SSL Slorth 0.897589 View
ENSG00000035928 RFC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.897483 View
ENSG00000127337 YEATS4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.897293 View
ENSG00000112658 SRF ENSG00000157764 BRAF H. sapiens SSL Slorth 0.897153 View
ENSG00000100351 GRAP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.897111 View
ENSG00000113013 HSPA9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.896762 View
ENSG00000112640 PPP2R5D ENSG00000157764 BRAF H. sapiens SSL Slorth 0.89636 View
ENSG00000157764 BRAF ENSG00000187109 NAP1L1 H. sapiens SSL Slorth 0.896295 View
ENSG00000137076 TLN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.896214 View
ENSG00000087095 NLK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.896138 View
ENSG00000072110 ACTN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.895711 View
ENSG00000101972 STAG2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.895685 View
ENSG00000143801 PSEN2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.895599 View
ENSG00000142655 PEX14 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.895461 View
ENSG00000103653 CSK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.89544 View
ENSG00000157764 BRAF ENSG00000164045 CDC25A H. sapiens SSL Slorth 0.895341 View
ENSG00000125450 NUP85 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.895203 View
ENSG00000138443 ABI2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.895182 View
ENSG00000152818 UTRN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894999 View
ENSG00000155508 CNOT8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894941 View
ENSG00000104969 SGTA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894901 View
ENSG00000103769 RAB11A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894894 View
ENSG00000108946 PRKAR1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894857 View
ENSG00000099381 SETD1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894841 View
ENSG00000157764 BRAF ENSG00000166266 CUL5 H. sapiens SSL Slorth 0.894656 View
ENSG00000128591 FLNC ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894633 View
ENSG00000132170 PPARG ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894381 View
ENSG00000075711 DLG1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.894257 View
ENSG00000157764 BRAF ENSG00000164754 RAD21 H. sapiens SSL Slorth 0.894196 View
ENSG00000157764 BRAF ENSG00000173327 MAP3K11 H. sapiens SSL Slorth 0.8941 View
ENSG00000157764 BRAF ENSG00000171960 PPIH H. sapiens SSL Slorth 0.894072 View
ENSG00000126524 SBDS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.893868 View
ENSG00000157764 BRAF ENSG00000176974 SHMT1 H. sapiens SSL Slorth 0.893622 View
ENSG00000131558 EXOC4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.893582 View
ENSG00000132664 POLR3F ENSG00000157764 BRAF H. sapiens SSL Slorth 0.893499 View