BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000175793 SFN H. sapiens SDL Slorth 0.902415 View
ENSG00000009413 REV3L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.902308 View
ENSG00000101849 TBL1X ENSG00000157764 BRAF H. sapiens SSL Slorth 0.901898 View
ENSG00000157764 BRAF ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.901816 View
ENSG00000065675 PRKCQ ENSG00000157764 BRAF H. sapiens SSL Slorth 0.901734 View
ENSG00000157764 BRAF ENSG00000248905 FMN1 H. sapiens SDL Slorth 0.901685 View
ENSG00000126561 STAT5A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.901642 View
ENSG00000157764 BRAF ENSG00000159259 CHAF1B H. sapiens SDL Slorth 0.901623 View
ENSG00000111653 ING4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.901546 View
ENSG00000130396 AFDN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.901542 View
ENSG00000157764 BRAF ENSG00000160294 MCM3AP H. sapiens SSL Slorth 0.901534 View
ENSG00000131467 PSME3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.901325 View
ENSG00000157764 BRAF ENSG00000170296 GABARAP H. sapiens SDL Slorth 0.901222 View
ENSG00000157764 BRAF ENSG00000163558 PRKCI H. sapiens SDL Slorth 0.901134 View
ENSG00000157764 BRAF ENSG00000197892 KIF13B H. sapiens SDL Slorth 0.901084 View
ENSG00000136937 NCBP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.901078 View
ENSG00000157764 BRAF ENSG00000183020 AP2A2 H. sapiens SSL Slorth 0.900781 View
ENSG00000157764 BRAF ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.900537 View
ENSG00000157764 BRAF ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.900537 View
ENSG00000157764 BRAF ENSG00000215021 PHB2 H. sapiens SSL Slorth 0.900403 View
ENSG00000157764 BRAF ENSG00000167815 PRDX2 H. sapiens SDL Slorth 0.900265 View
ENSG00000128052 KDR ENSG00000157764 BRAF H. sapiens SDL Slorth 0.900232 View
ENSG00000123159 GIPC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.900087 View
ENSG00000119707 RBM25 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.900011 View
ENSG00000119335 SET ENSG00000157764 BRAF H. sapiens SSL Slorth 0.899913 View
ENSG00000070770 CSNK2A2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.899496 View
ENSG00000110713 NUP98 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.899433 View
ENSG00000147416 ATP6V1B2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.899325 View
ENSG00000065427 KARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.899273 View
ENSG00000157764 BRAF ENSG00000172757 CFL1 H. sapiens SSL Slorth 0.899037 View
ENSG00000072958 AP1M1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.899013 View
ENSG00000157764 BRAF ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.89894 View
ENSG00000151532 VTI1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.898838 View
ENSG00000148606 POLR3A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.898667 View
ENSG00000092108 SCFD1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.898616 View
ENSG00000157764 BRAF ENSG00000159461 AMFR H. sapiens SSL Slorth 0.898585 View
ENSG00000110321 EIF4G2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.89848 View
ENSG00000108587 GOSR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.898443 View
ENSG00000138071 ACTR2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.898199 View
ENSG00000105402 NAPA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.898123 View