BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000176105 YES1 H. sapiens SDL Slorth 0.905188 View
ENSG00000150459 SAP18 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.905179 View
ENSG00000072518 MARK2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.905107 View
ENSG00000126457 PRMT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.904891 View
ENSG00000157764 BRAF ENSG00000166226 CCT2 H. sapiens SDL Slorth 0.904881 View
ENSG00000157764 BRAF ENSG00000167965 MLST8 H. sapiens SSL Slorth 0.904867 View
ENSG00000100239 PPP6R2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.904848 View
ENSG00000085415 SEH1L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.904786 View
ENSG00000107282 APBA1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.904764 View
ENSG00000108262 GIT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.904726 View
ENSG00000141968 VAV1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.904577 View
ENSG00000101132 PFDN4 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.904455 View
ENSG00000157764 BRAF ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.904441 View
ENSG00000157764 BRAF ENSG00000196611 MMP1 H. sapiens SDL Slorth 0.904415 View
ENSG00000065548 ZC3H15 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.904332 View
ENSG00000157764 BRAF ENSG00000189403 HMGB1 H. sapiens SDL Slorth 0.904229 View
ENSG00000157764 BRAF ENSG00000166197 NOLC1 H. sapiens SSL Slorth 0.904176 View
ENSG00000151150 ANK3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.904069 View
ENSG00000112685 EXOC2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.904032 View
ENSG00000101109 STK4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.903905 View
ENSG00000118503 TNFAIP3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.903871 View
ENSG00000116044 NFE2L2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.903769 View
ENSG00000133316 WDR74 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90375 View
ENSG00000157764 BRAF ENSG00000170296 GABARAP H. sapiens SSL Slorth 0.903649 View
ENSG00000122692 SMU1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.903592 View
ENSG00000157764 BRAF ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.903534 View
ENSG00000141384 TAF4B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.903451 View
ENSG00000157764 BRAF ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.903155 View
ENSG00000108384 RAD51C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.903146 View
ENSG00000108298 RPL19 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.903133 View
ENSG00000157764 BRAF ENSG00000165609 NUDT5 H. sapiens SSL Slorth 0.903005 View
ENSG00000157764 BRAF ENSG00000177084 POLE H. sapiens SSL Slorth 0.902923 View
ENSG00000114554 PLXNA1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.902864 View
ENSG00000134982 APC ENSG00000157764 BRAF H. sapiens SDL Slorth 0.902858 View
ENSG00000072803 FBXW11 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.902755 View
ENSG00000118689 FOXO3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.902672 View
ENSG00000157764 BRAF ENSG00000197579 TOPORS H. sapiens SSL Slorth 0.90252 View
ENSG00000101811 CSTF2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.902509 View
ENSG00000008018 PSMB1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.902507 View
ENSG00000157764 BRAF ENSG00000184304 PRKD1 H. sapiens SDL Slorth 0.902462 View