BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000123737 EXOSC9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.912773 View
ENSG00000157764 BRAF ENSG00000163161 ERCC3 H. sapiens SSL Slorth 0.91266 View
ENSG00000134001 EIF2S1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.91255 View
ENSG00000108953 YWHAE ENSG00000157764 BRAF H. sapiens SDL Slorth 0.912172 View
ENSG00000077380 DYNC1I2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.911924 View
ENSG00000092529 CAPN3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.91192 View
ENSG00000054116 TRAPPC3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.911863 View
ENSG00000114867 EIF4G1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.91181 View
ENSG00000157764 BRAF ENSG00000198700 IPO9 H. sapiens SSL Slorth 0.911798 View
ENSG00000157764 BRAF ENSG00000169554 ZEB2 H. sapiens SDL Slorth 0.911792 View
ENSG00000157764 BRAF ENSG00000198373 WWP2 H. sapiens SSL Slorth 0.91175 View
ENSG00000157764 BRAF ENSG00000166670 MMP10 H. sapiens SDL Slorth 0.911636 View
ENSG00000122512 PMS2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.911418 View
ENSG00000122565 CBX3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.91119 View
ENSG00000127955 GNAI1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.911162 View
ENSG00000102225 CDK16 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.911127 View
ENSG00000130985 UBA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.910346 View
ENSG00000157764 BRAF ENSG00000166592 RRAD H. sapiens SDL Slorth 0.91028 View
ENSG00000132612 VPS4A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.910241 View
ENSG00000157764 BRAF ENSG00000164022 AIMP1 H. sapiens SSL Slorth 0.910225 View
ENSG00000035403 VCL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.910186 View
ENSG00000112592 TBP ENSG00000157764 BRAF H. sapiens SDL Slorth 0.909971 View
ENSG00000157764 BRAF ENSG00000163947 ARHGEF3 H. sapiens SDL Slorth 0.909898 View
ENSG00000114062 UBE3A ENSG00000157764 BRAF H. sapiens SDL Slorth 0.909829 View
ENSG00000063244 U2AF2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90981 View
ENSG00000134440 NARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90951 View
ENSG00000135250 SRPK2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.909379 View
ENSG00000157764 BRAF ENSG00000165684 SNAPC4 H. sapiens SDL Slorth 0.909345 View
ENSG00000157764 BRAF ENSG00000159251 ACTC1 H. sapiens SDL Slorth 0.909265 View
ENSG00000101361 NOP56 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.909113 View
ENSG00000137413 TAF8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908762 View
ENSG00000106211 HSPB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90868 View
ENSG00000092531 SNAP23 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908644 View
ENSG00000157764 BRAF ENSG00000183741 CBX6 H. sapiens SDL Slorth 0.908599 View
ENSG00000049246 PER3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908322 View
ENSG00000157764 BRAF ENSG00000197157 SND1 H. sapiens SDL Slorth 0.90832 View
ENSG00000096063 SRPK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908315 View
ENSG00000144848 ATG3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908293 View
ENSG00000114767 RRP9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908094 View
ENSG00000155111 CDK19 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.908089 View