PMS2 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PMS2	ENSG00000122512	colorectal endometrial ovarian medulloblastoma glioma	No drugs in record	DNA binding endonuclease activity protein binding ATP binding ATPase activity single base insertion or deletion binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding	PMS1 (S. cerevisiae) Pms2 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)