BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000116473 RAP1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.893355 View
ENSG00000101336 HCK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.893134 View
ENSG00000047932 GOPC ENSG00000157764 BRAF H. sapiens SSL Slorth 0.893084 View
ENSG00000111877 MCM9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892891 View
ENSG00000070061 IKBKAP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892818 View
ENSG00000105197 TIMM50 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892737 View
ENSG00000079785 DDX1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892668 View
ENSG00000143256 PFDN2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892592 View
ENSG00000157764 BRAF ENSG00000171223 JUNB H. sapiens SSL Slorth 0.892342 View
ENSG00000138107 ACTR1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892327 View
ENSG00000086065 CHMP5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892038 View
ENSG00000110107 PRPF19 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.892037 View
ENSG00000101421 CHMP4B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891957 View
ENSG00000130725 UBE2M ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891936 View
ENSG00000100227 POLDIP3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891835 View
ENSG00000078043 PIAS2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891766 View
ENSG00000084774 CAD ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891716 View
ENSG00000105011 ASF1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891709 View
ENSG00000133627 ACTR3B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891656 View
ENSG00000092847 AGO1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891605 View
ENSG00000077097 TOP2B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891292 View
ENSG00000157764 BRAF ENSG00000159352 PSMD4 H. sapiens SSL Slorth 0.891207 View
ENSG00000131508 UBE2D2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.891207 View
ENSG00000157764 BRAF ENSG00000198554 WDHD1 H. sapiens SSL Slorth 0.890973 View
ENSG00000127022 CANX ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890934 View
ENSG00000132906 CASP9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890933 View
ENSG00000157764 BRAF ENSG00000175029 CTBP2 H. sapiens SSL Slorth 0.890929 View
ENSG00000147044 CASK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890899 View
ENSG00000125107 CNOT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890725 View
ENSG00000148229 POLE3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890723 View
ENSG00000130713 EXOSC2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890373 View
ENSG00000074181 NOTCH3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890314 View
ENSG00000019995 ZRANB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.89025 View
ENSG00000108055 SMC3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890168 View
ENSG00000157764 BRAF ENSG00000164867 NOS3 H. sapiens SSL Slorth 0.89014 View
ENSG00000100083 GGA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.890124 View
ENSG00000157764 BRAF ENSG00000163482 STK36 H. sapiens SSL Slorth 0.889996 View
ENSG00000157764 BRAF ENSG00000221829 FANCG H. sapiens SSL Slorth 0.88986 View
ENSG00000095951 HIVEP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.889831 View
ENSG00000101367 MAPRE1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.88957 View