BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000111424 VDR ENSG00000157764 BRAF H. sapiens SSL Slorth 0.77208 View
ENSG00000126858 RHOT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.771603 View
ENSG00000076944 STXBP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.771388 View
ENSG00000105364 MRPL4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.770972 View
ENSG00000157764 BRAF ENSG00000173801 JUP H. sapiens SSL Slorth 0.770651 View
ENSG00000071537 SEL1L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.770386 View
ENSG00000136931 NR5A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.770314 View
ENSG00000134987 WDR36 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.770182 View
ENSG00000157764 BRAF ENSG00000182199 SHMT2 H. sapiens SSL Slorth 0.77003 View
ENSG00000157764 BRAF ENSG00000182287 AP1S2 H. sapiens SSL Slorth 0.769837 View
ENSG00000157764 BRAF ENSG00000165527 ARF6 H. sapiens SSL Slorth 0.76927 View
ENSG00000157764 BRAF ENSG00000198873 GRK5 H. sapiens SSL Slorth 0.769175 View
ENSG00000112079 STK38 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.76912 View
ENSG00000157764 BRAF ENSG00000166794 PPIB H. sapiens SSL Slorth 0.769111 View
ENSG00000085276 MECOM ENSG00000157764 BRAF H. sapiens SSL Slorth 0.768591 View
ENSG00000129084 PSMA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.768586 View
ENSG00000065000 AP3D1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.768552 View
ENSG00000131165 CHMP1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.768485 View
ENSG00000157764 BRAF ENSG00000163931 TKT H. sapiens SSL Slorth 0.767832 View
ENSG00000157764 BRAF ENSG00000184445 KNTC1 H. sapiens SSL Slorth 0.767359 View
ENSG00000157764 BRAF ENSG00000178184 PARD6G H. sapiens SSL Slorth 0.767335 View
ENSG00000157764 BRAF ENSG00000163629 PTPN13 H. sapiens SSL Slorth 0.767104 View
ENSG00000157764 BRAF ENSG00000164815 ORC5 H. sapiens SSL Slorth 0.766995 View
ENSG00000151491 EPS8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.766803 View
ENSG00000157764 BRAF ENSG00000166900 STX3 H. sapiens SSL Slorth 0.766471 View
ENSG00000073536 NLE1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.766438 View
ENSG00000157764 BRAF ENSG00000163251 FZD5 H. sapiens SSL Slorth 0.765929 View
ENSG00000157764 BRAF ENSG00000168214 RBPJ H. sapiens SSL Slorth 0.76588 View
ENSG00000157764 BRAF ENSG00000184979 USP18 H. sapiens SSL Slorth 0.76577 View
ENSG00000157764 BRAF ENSG00000182606 TRAK1 H. sapiens SSL Slorth 0.765522 View
ENSG00000100650 SRSF5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.765244 View
ENSG00000100813 ACIN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.765028 View
ENSG00000131711 MAP1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.765013 View
ENSG00000113368 LMNB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.764998 View
ENSG00000157764 BRAF ENSG00000182132 KCNIP1 H. sapiens SSL Slorth 0.764704 View
ENSG00000157764 BRAF ENSG00000173846 PLK3 H. sapiens SSL Slorth 0.76437 View
ENSG00000011304 PTBP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.764102 View
ENSG00000078053 AMPH ENSG00000157764 BRAF H. sapiens SSL Slorth 0.764067 View
ENSG00000157764 BRAF ENSG00000182541 LIMK2 H. sapiens SSL Slorth 0.764036 View
ENSG00000157764 BRAF ENSG00000189056 RELN H. sapiens SSL Slorth 0.763963 View