BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000092621 PHGDH ENSG00000157764 BRAF H. sapiens SSL Slorth 0.78014 View
ENSG00000157764 BRAF ENSG00000204389 HSPA1A H. sapiens SSL Slorth 0.780108 View
ENSG00000157764 BRAF ENSG00000215114 UBXN2B H. sapiens SSL Slorth 0.779943 View
ENSG00000137574 TGS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.77988 View
ENSG00000104320 NBN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.779777 View
ENSG00000157764 BRAF ENSG00000197892 KIF13B H. sapiens SSL Slorth 0.779482 View
ENSG00000055044 NOP58 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.779254 View
ENSG00000157764 BRAF ENSG00000169251 NMD3 H. sapiens SSL Slorth 0.77883 View
ENSG00000157764 BRAF ENSG00000168411 RFWD3 H. sapiens SSL Slorth 0.778402 View
ENSG00000157764 BRAF ENSG00000179295 PTPN11 H. sapiens SSL Slorth 0.778231 View
ENSG00000131899 LLGL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.778145 View
ENSG00000157764 BRAF ENSG00000169439 SDC2 H. sapiens SSL Slorth 0.778103 View
ENSG00000113141 IK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.778056 View
ENSG00000126934 MAP2K2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.778053 View
ENSG00000112742 TTK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.777601 View
ENSG00000156508 EEF1A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.777587 View
ENSG00000157764 BRAF ENSG00000166484 MAPK7 H. sapiens SSL Slorth 0.776875 View
ENSG00000068654 POLR1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.776817 View
ENSG00000157764 BRAF ENSG00000166349 RAG1 H. sapiens SSL Slorth 0.776458 View
ENSG00000157764 BRAF ENSG00000188603 CLN3 H. sapiens SSL Slorth 0.776362 View
ENSG00000117751 PPP1R8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.77627 View
ENSG00000114738 MAPKAPK3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.776093 View
ENSG00000157764 BRAF ENSG00000177169 ULK1 H. sapiens SSL Slorth 0.775976 View
ENSG00000106144 CASP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.775385 View
ENSG00000139718 SETD1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.775307 View
ENSG00000157764 BRAF ENSG00000249915 PDCD6 H. sapiens SSL Slorth 0.775242 View
ENSG00000135476 ESPL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.775082 View
ENSG00000086061 DNAJA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.774987 View
ENSG00000129219 PLD2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.774854 View
ENSG00000157764 BRAF ENSG00000162298 SYVN1 H. sapiens SSL Slorth 0.774715 View
ENSG00000112249 ASCC3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.774286 View
ENSG00000157764 BRAF ENSG00000180228 PRKRA H. sapiens SSL Slorth 0.774189 View
ENSG00000123416 TUBA1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.774012 View
ENSG00000131263 RLIM ENSG00000157764 BRAF H. sapiens SSL Slorth 0.773691 View
ENSG00000157764 BRAF ENSG00000162302 RPS6KA4 H. sapiens SSL Slorth 0.773612 View
ENSG00000113282 CLINT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.773228 View
ENSG00000137054 POLR1E ENSG00000157764 BRAF H. sapiens SSL Slorth 0.773046 View
ENSG00000102471 NDFIP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.772896 View
ENSG00000157764 BRAF ENSG00000175931 UBE2O H. sapiens SSL Slorth 0.772441 View
ENSG00000115306 SPTBN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.772303 View