ACVR2A - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ACVR2A	ENSG00000121989	large intestine carcinoma stomach carcinoma pancreatic carcinoma biliary tract oesophagus	No drugs in record	protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity protein binding ATP binding coreceptor activity growth factor binding PDZ domain binding inhibin binding protein self-association metal ion binding BMP receptor activity activin-activated receptor activity activin binding	put (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)