JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077080 ACTL6B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.762218 View
ENSG00000138795 LEF1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.762128 View
ENSG00000004478 FKBP4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.762035 View
ENSG00000156709 AIFM1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.761947 View
ENSG00000009335 UBE3C ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.761919 View
ENSG00000133119 RFC3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.761797 View
ENSG00000020922 MRE11 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.761745 View
ENSG00000135100 HNF1A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.761403 View
ENSG00000161956 SENP3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.761006 View
ENSG00000117528 ABCD3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.760435 View
ENSG00000162434 JAK1 ENSG00000184009 ACTG1 H. sapiens SSL Slorth 0.760184 View
ENSG00000162434 JAK1 ENSG00000163931 TKT H. sapiens SSL Slorth 0.759905 View
ENSG00000065135 GNAI3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.759552 View
ENSG00000113282 CLINT1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.759351 View
ENSG00000128340 RAC2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.759249 View
ENSG00000113658 SMAD5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.759231 View
ENSG00000087470 DNM1L ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.759083 View
ENSG00000162434 JAK1 ENSG00000183955 KMT5A H. sapiens SSL Slorth 0.7588 View
ENSG00000105063 PPP6R1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.758651 View
ENSG00000162434 JAK1 ENSG00000168646 AXIN2 H. sapiens SSL Slorth 0.75859 View
ENSG00000162434 JAK1 ENSG00000182774 RPS17 H. sapiens SSL Slorth 0.75855 View
ENSG00000085276 MECOM ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.75852 View
ENSG00000121067 SPOP ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.758394 View
ENSG00000115738 ID2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.758339 View
ENSG00000105229 PIAS4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.758158 View
ENSG00000162434 JAK1 ENSG00000162924 REL H. sapiens SSL Slorth 0.758073 View
ENSG00000100813 ACIN1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.757869 View
ENSG00000134250 NOTCH2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.757652 View
ENSG00000144028 SNRNP200 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.757581 View
ENSG00000129993 CBFA2T3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.75754 View
ENSG00000100138 SNU13 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.75738 View
ENSG00000162434 JAK1 ENSG00000167815 PRDX2 H. sapiens SSL Slorth 0.757085 View
ENSG00000070669 ASNS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.757046 View
ENSG00000113300 CNOT6 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.756748 View
ENSG00000082781 ITGB5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.75647 View
ENSG00000090273 NUDC ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.756263 View
ENSG00000162434 JAK1 ENSG00000168411 RFWD3 H. sapiens SSL Slorth 0.75623 View
ENSG00000162434 JAK1 ENSG00000205220 PSMB10 H. sapiens SSL Slorth 0.756168 View
ENSG00000162434 JAK1 ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.75609 View
ENSG00000113916 BCL6 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.756013 View