JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000134070 IRAK2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.820943 View
ENSG00000096746 HNRNPH3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.82089 View
ENSG00000004660 CAMKK1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.820881 View
ENSG00000120656 TAF12 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.820807 View
ENSG00000162434 JAK1 ENSG00000181449 SOX2 H. sapiens SSL Slorth 0.820339 View
ENSG00000162434 JAK1 ENSG00000173674 EIF1AX H. sapiens SSL Slorth 0.820295 View
ENSG00000063245 EPN1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.81978 View
ENSG00000161960 EIF4A1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.818955 View
ENSG00000162434 JAK1 ENSG00000175334 BANF1 H. sapiens SSL Slorth 0.818529 View
ENSG00000162434 JAK1 ENSG00000168522 FNTA H. sapiens SSL Slorth 0.818255 View
ENSG00000162434 JAK1 ENSG00000185344 ATP6V0A2 H. sapiens SSL Slorth 0.817971 View
ENSG00000162434 JAK1 ENSG00000165458 INPPL1 H. sapiens SSL Slorth 0.817934 View
ENSG00000083799 CYLD ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.817732 View
ENSG00000162434 JAK1 ENSG00000185122 HSF1 H. sapiens SSL Slorth 0.817688 View
ENSG00000112715 VEGFA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.816758 View
ENSG00000134899 ERCC5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.816755 View
ENSG00000111361 EIF2B1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.81655 View
ENSG00000118515 SGK1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.816336 View
ENSG00000126934 MAP2K2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.816199 View
ENSG00000162434 JAK1 ENSG00000198286 CARD11 H. sapiens SSL Slorth 0.815698 View
ENSG00000162434 JAK1 ENSG00000198033 TUBA3C H. sapiens SSL Slorth 0.815553 View
ENSG00000162434 JAK1 ENSG00000167460 TPM4 H. sapiens SSL Slorth 0.815459 View
ENSG00000122218 COPA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.815454 View
ENSG00000115866 DARS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.814924 View
ENSG00000155974 GRIP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.814823 View
ENSG00000162434 JAK1 ENSG00000164056 SPRY1 H. sapiens SSL Slorth 0.814591 View
ENSG00000120738 EGR1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.814548 View
ENSG00000136504 KAT7 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.813889 View
ENSG00000125630 POLR1B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.813589 View
ENSG00000162434 JAK1 ENSG00000170144 HNRNPA3 H. sapiens SSL Slorth 0.81349 View
ENSG00000008128 CDK11A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.813329 View
ENSG00000104907 TRMT1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.813232 View
ENSG00000140682 TGFB1I1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.813145 View
ENSG00000162434 JAK1 ENSG00000184979 USP18 H. sapiens SSL Slorth 0.813125 View
ENSG00000120063 GNA13 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.812976 View
ENSG00000162434 JAK1 ENSG00000167965 MLST8 H. sapiens SSL Slorth 0.812939 View
ENSG00000090376 IRAK3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.812806 View
ENSG00000105221 AKT2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.812752 View
ENSG00000108561 C1QBP ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.812683 View
ENSG00000162434 JAK1 ENSG00000164032 H2AFZ H. sapiens SSL Slorth 0.812581 View