JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000104320 NBN ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.796345 View
ENSG00000111596 CNOT2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.796039 View
ENSG00000162434 JAK1 ENSG00000184675 AMER1 H. sapiens SSL Slorth 0.795959 View
ENSG00000107295 SH3GL2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.795474 View
ENSG00000148737 TCF7L2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.795442 View
ENSG00000133706 LARS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.795431 View
ENSG00000112249 ASCC3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.795342 View
ENSG00000100650 SRSF5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.795274 View
ENSG00000162434 JAK1 ENSG00000197451 HNRNPAB H. sapiens SSL Slorth 0.79503 View
ENSG00000122691 TWIST1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.7947 View
ENSG00000159459 UBR1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.794508 View
ENSG00000067225 PKM ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.794209 View
ENSG00000162434 JAK1 ENSG00000166869 CHP2 H. sapiens SSL Slorth 0.794082 View
ENSG00000162434 JAK1 ENSG00000215021 PHB2 H. sapiens SSL Slorth 0.793745 View
ENSG00000132388 UBE2G1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.793698 View
ENSG00000131828 PDHA1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.793303 View
ENSG00000162434 JAK1 ENSG00000172757 CFL1 H. sapiens SSL Slorth 0.793161 View
ENSG00000120705 ETF1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.793009 View
ENSG00000162434 JAK1 ENSG00000178209 PLEC H. sapiens SSL Slorth 0.792919 View
ENSG00000119318 RAD23B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.792361 View
ENSG00000108312 UBTF ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.792217 View
ENSG00000129084 PSMA1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.791823 View
ENSG00000112081 SRSF3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.791028 View
ENSG00000149792 MRPL49 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.79101 View
ENSG00000162434 JAK1 ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.790875 View
ENSG00000153107 ANAPC1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.790839 View
ENSG00000160867 FGFR4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.790832 View
ENSG00000162434 JAK1 ENSG00000169756 LIMS1 H. sapiens SSL Slorth 0.790681 View
ENSG00000113643 RARS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.790463 View
ENSG00000147274 RBMX ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.790343 View
ENSG00000102554 KLF5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.789725 View
ENSG00000127564 PKMYT1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.789468 View
ENSG00000162434 JAK1 ENSG00000175029 CTBP2 H. sapiens SSL Slorth 0.78861 View
ENSG00000280548 FBL ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.787957 View
ENSG00000140455 USP3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.787945 View
ENSG00000073282 TP63 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.787783 View
ENSG00000162434 JAK1 ENSG00000173846 PLK3 H. sapiens SSL Slorth 0.787757 View
ENSG00000162434 JAK1 ENSG00000186153 WWOX H. sapiens SSL Slorth 0.78756 View
ENSG00000162434 JAK1 ENSG00000238134 EHMT2 H. sapiens SSL Slorth 0.787521 View
ENSG00000162434 JAK1 ENSG00000172409 CLP1 H. sapiens SSL Slorth 0.787486 View