JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000162434 JAK1 ENSG00000182504 CEP97 H. sapiens SSL Slorth 0.805592 View
ENSG00000095002 MSH2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.805311 View
ENSG00000134014 ELP3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.805247 View
ENSG00000057657 PRDM1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.805116 View
ENSG00000104856 RELB ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.804949 View
ENSG00000066777 ARFGEF1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.804873 View
ENSG00000135476 ESPL1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.804822 View
ENSG00000047410 TPR ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.80478 View
ENSG00000101557 USP14 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.804732 View
ENSG00000100934 SEC23A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.804715 View
ENSG00000112742 TTK ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.804314 View
ENSG00000162434 JAK1 ENSG00000166333 ILK H. sapiens SSL Slorth 0.803878 View
ENSG00000068654 POLR1A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.80371 View
ENSG00000158290 CUL4B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.803422 View
ENSG00000139343 SNRPF ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.803382 View
ENSG00000133627 ACTR3B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.803275 View
ENSG00000112578 BYSL ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.803267 View
ENSG00000140443 IGF1R ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.803087 View
ENSG00000075413 MARK3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.803008 View
ENSG00000162434 JAK1 ENSG00000197157 SND1 H. sapiens SSL Slorth 0.802354 View
ENSG00000131711 MAP1B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.80213 View
ENSG00000141030 COPS3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.802125 View
ENSG00000162434 JAK1 ENSG00000198087 CD2AP H. sapiens SSL Slorth 0.801882 View
ENSG00000141867 BRD4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.801853 View
ENSG00000152086 TUBA3E ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.801843 View
ENSG00000100401 RANGAP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.801603 View
ENSG00000099381 SETD1A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.801374 View
ENSG00000162434 JAK1 ENSG00000167996 FTH1 H. sapiens SSL Slorth 0.801211 View
ENSG00000155827 RNF20 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.799738 View
ENSG00000028528 SNX1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.799558 View
ENSG00000162434 JAK1 ENSG00000163041 H3F3A H. sapiens SSL Slorth 0.798944 View
ENSG00000116141 MARK1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.79837 View
ENSG00000126458 RRAS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.798199 View
ENSG00000162434 JAK1 ENSG00000197879 MYO1C H. sapiens SSL Slorth 0.79783 View
ENSG00000162434 JAK1 ENSG00000176248 ANAPC2 H. sapiens SSL Slorth 0.79698 View
ENSG00000162434 JAK1 ENSG00000166595 FAM96B H. sapiens SSL Slorth 0.796911 View
ENSG00000162434 JAK1 ENSG00000198677 TTC37 H. sapiens SSL Slorth 0.796654 View
ENSG00000101871 MID1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.796648 View
ENSG00000162434 JAK1 ENSG00000239672 NME1 H. sapiens SSL Slorth 0.796409 View
ENSG00000162434 JAK1 ENSG00000198648 STK39 H. sapiens SSL Slorth 0.796402 View