JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000162434 JAK1 ENSG00000172315 TP53RK H. sapiens SSL Slorth 0.78745 View
ENSG00000162434 JAK1 ENSG00000168439 STIP1 H. sapiens SSL Slorth 0.787368 View
ENSG00000162434 JAK1 ENSG00000184432 COPB2 H. sapiens SSL Slorth 0.787253 View
ENSG00000064995 TAF11 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.787164 View
ENSG00000162434 JAK1 ENSG00000182621 PLCB1 H. sapiens SSL Slorth 0.786894 View
ENSG00000086061 DNAJA1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.78679 View
ENSG00000162409 PRKAA2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.786535 View
ENSG00000143801 PSEN2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.786524 View
ENSG00000142875 PRKACB ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.786422 View
ENSG00000137822 TUBGCP4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.786337 View
ENSG00000162434 JAK1 ENSG00000196911 KPNA5 H. sapiens SSL Slorth 0.786095 View
ENSG00000104885 DOT1L ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.785993 View
ENSG00000111642 CHD4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.785645 View
ENSG00000090060 PAPOLA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.785595 View
ENSG00000162434 JAK1 ENSG00000166803 KIAA0101 H. sapiens SSL Slorth 0.785526 View
ENSG00000101945 SUV39H1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.785421 View
ENSG00000162434 JAK1 ENSG00000196586 MYO6 H. sapiens SSL Slorth 0.784862 View
ENSG00000162434 JAK1 ENSG00000169696 ASPSCR1 H. sapiens SSL Slorth 0.784466 View
ENSG00000101751 POLI ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.784365 View
ENSG00000122545 SEPT7 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.784074 View
ENSG00000124535 WRNIP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.783621 View
ENSG00000080839 RBL1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.782815 View
ENSG00000162434 JAK1 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.782636 View
ENSG00000162434 JAK1 ENSG00000170485 NPAS2 H. sapiens SSL Slorth 0.782309 View
ENSG00000070367 EXOC5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.782271 View
ENSG00000119414 PPP6C ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.78193 View
ENSG00000113615 SEC24A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.781848 View
ENSG00000158022 TRIM63 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.781798 View
ENSG00000156304 SCAF4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.781074 View
ENSG00000162434 JAK1 ENSG00000163482 STK36 H. sapiens SSL Slorth 0.780915 View
ENSG00000162434 JAK1 ENSG00000170242 USP47 H. sapiens SSL Slorth 0.780892 View
ENSG00000162434 JAK1 ENSG00000168421 RHOH H. sapiens SSL Slorth 0.780876 View
ENSG00000162434 JAK1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.780779 View
ENSG00000162434 JAK1 ENSG00000164134 NAA15 H. sapiens SSL Slorth 0.780449 View
ENSG00000126803 HSPA2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.780305 View
ENSG00000143476 DTL ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.778835 View
ENSG00000113263 ITK ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.778684 View
ENSG00000124222 STX16 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.778339 View
ENSG00000162434 JAK1 ENSG00000198947 DMD H. sapiens SSL Slorth 0.778157 View
ENSG00000083168 KAT6A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.777444 View