JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000162434 JAK1 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.941682 View
ENSG00000080224 EPHA6 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.941659 View
ENSG00000113712 CSNK1A1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.941594 View
ENSG00000148429 USP6NL ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.941546 View
ENSG00000162434 JAK1 ENSG00000173209 AHSA2 H. sapiens SDL Slorth 0.941396 View
ENSG00000026103 FAS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.941258 View
ENSG00000162434 JAK1 ENSG00000165025 SYK H. sapiens SSL Slorth 0.941115 View
ENSG00000162434 JAK1 ENSG00000170248 PDCD6IP H. sapiens SSL Slorth 0.940872 View
ENSG00000149781 FERMT3 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000138594 TMOD3 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000140199 SLC12A6 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000115616 SLC9A2 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000085185 BCORL1 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000153132 CLGN ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000100228 RAB36 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940861 View
ENSG00000140464 PML ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940854 View
ENSG00000114315 HES1 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940799 View
ENSG00000147647 DPYS ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940638 View
ENSG00000144644 GADL1 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940638 View
ENSG00000129691 ASH2L ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940636 View
ENSG00000135018 UBQLN1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940562 View
ENSG00000100906 NFKBIA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940487 View
ENSG00000070404 FSTL3 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940457 View
ENSG00000144668 ITGA9 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940445 View
ENSG00000101966 XIAP ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940434 View
ENSG00000148835 TAF5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940415 View
ENSG00000100644 HIF1A ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940369 View
ENSG00000070159 PTPN3 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940359 View
ENSG00000105737 GRIK5 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940309 View
ENSG00000101412 E2F1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940238 View
ENSG00000162434 JAK1 ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.94018 View
ENSG00000162434 JAK1 ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.94018 View
ENSG00000010671 BTK ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940155 View
ENSG00000138069 RAB1A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940094 View
ENSG00000106462 EZH2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.94008 View
ENSG00000077721 UBE2A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.94007 View
ENSG00000117748 RPA2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940063 View
ENSG00000150753 CCT5 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.940015 View
ENSG00000162434 JAK1 ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.939959 View
ENSG00000126561 STAT5A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.939859 View