XIAP - JAK1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XIAP	ENSG00000101966	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity identical protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process ubiquitin protein ligase activity	Diap2 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)