DPYS - JAK1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DPYS	ENSG00000147647	No diseases in record	No drugs in record	uracil binding thymine binding dihydropyrimidinase activity zinc ion binding amino acid binding phosphoprotein binding	DAL1 (S. cerevisiae) dhp-1 (C. elegans) dhp-2 (C. elegans) CRMP (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)